伴对侧耳感音神经性聋的突发性聋患者临床特征分析

发布时间：2018-01-01 18:06

本文关键词：伴对侧耳感音神经性聋的突发性聋患者临床特征分析　出处：《临床耳鼻咽喉头颈外科杂志》2016年14期 　论文类型：期刊论文

【摘要】：目的:分析伴对侧耳感音神经性聋的突发性聋患者的临床特征及预后效果,了解与该病发生及影响预后的相关因素。方法:对63例伴对侧感音神经性聋的突发性聋患者的临床资料进行系统性分析,包括临床表现、听力学检查、疗效评估以及对侧耳临床特征等,与同时起病双侧突发性聋和单侧突发性聋组资料对比,分析致病和影响预后的危险因素,总结该病发生、发展及转归的特点。结果:63例患者占本研究763例突发性聋患者的8.3%,男性大于女性,伴发眩晕比例和患有高血糖、高血脂的比例显著高于其他两组,现患耳听力损失程度分布以及听力曲线类型与单侧突发性聋组差异有统计学意义(P0.05),但与双侧突发性聋组差异无统计学意义(P0.05)。59%的患者为对侧耳听力下降2~10年内出现现患耳的突发性聋。对侧耳听力损失的病史中突发性聋比例最高(49%)。现患耳治疗总有效率为14.3%,与双侧突发性聋组差异无统计学意义(P0.05),单侧突发性聋组治疗总有效率为62.8%,明显高于其他2组,差异有统计学意义(P0.01)。对侧耳极重度或重度感音神经性聋的患者42例,现患耳治疗后总有效率为9.5%,低于对侧耳中重度和中度耳聋患者的23.8%,差异有统计学意义(P0.05)。结论:伴对侧耳感音神经性聋的突发性聋发病原因复杂,预后较差,尤其对侧耳极重度或重度感音神经性聋的患者,严重影响言语与生活质量,对急性期药物治疗后无效的病例需制定后续个性化听力康复治疗方案。
[Abstract]:Objective: to analyze the clinical features and prognosis of sudden deafness with contralateral sensorineural hearing loss. Methods: the clinical data of 63 cases of sudden deafness with contralateral sensorineural deafness were analyzed systematically, including clinical manifestation and audiological examination. The evaluation of curative effect and the clinical characteristics of lateral ear were compared with the data of bilateral sudden deafness and unilateral sudden deafness at the same time, the risk factors of pathogenicity and prognosis were analyzed, and the occurrence of the disease was summarized. Results of 763 patients with sudden deafness in this study, 8.3% of them were male than female, accompanied by vertigo and hyperglycemia. The proportion of hyperlipidemia was significantly higher than that of the other two groups. The distribution of hearing loss and the type of hearing curve were significantly different from those of unilateral sudden deafness group (P 0.05). But there was no significant difference between bilateral sudden deafness group and bilateral sudden deafness group (P0.05). 59% of the patients had sudden deafness of the affected ears within 2 to 10 years. The highest proportion of sudden deafness in the history of hearing loss in the opposite ears was 49%. The total effective rate of ototherapy is 14.3%. There was no significant difference between unilateral sudden deafness group and bilateral sudden deafness group (P 0.05). The total effective rate of unilateral sudden deafness group was 62.8, which was significantly higher than that of the other two groups. The total effective rate of 42 patients with severe or severe sensorineural deafness was 9.5%. The difference was statistically significant (P 0.05). Conclusion: the causes of sudden deafness with contralateral sensorineural hearing loss are complex and the prognosis is poor. Especially for the patients with severe or severe sensorineural hearing loss, speech and quality of life are seriously affected.
【作者单位】：中山大学孙逸仙纪念医院耳鼻咽喉科中山大学听力与言语研究所;深圳市光明新区中心医院耳鼻咽喉科;
【基金】：广东省科技计划项目(No:2014A020212097) 科技部“十二五”科技支撑计划(No:201213A112B02)
【分类号】：R764.437
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