原发性开角型青光眼患者确诊时视野损害程度的相关因素分析

发布时间：2018-01-03 22:27

本文关键词：原发性开角型青光眼患者确诊时视野损害程度的相关因素分析　出处：《眼科新进展》2016年04期 　论文类型：期刊论文

【摘要】：目的分析原发性开角型青光眼(primary open-angle glaucoma,POAG)患者确诊时的视野损害程度及其相关因素。方法收集2014年5月至2015年10月在我院门诊就诊的POAG患者113例113眼。根据视野损害分级将患者分为早期视野损害组(视野损害0~1级)和中晚期视野损害组(视野损害2~5级)。对两组患者的确诊年龄、性别、身体质量指数、青光眼相关症状、家族史、高度近视、中央角膜厚度、眼压等相关因素进行统计分析。结果早期视野损害组31眼(27.43%),中晚期视野损害组82眼(72.57%)。早期视野损害组的确诊年龄为(52.81±16.57)岁,眼压为(23.67±11.44)mm Hg(1 kPa=7.5 mmHg),与中晚期视野损害组的(45.62±17.12)岁和(30.58±12.13)mm Hg相比,差异均有统计学意义(P=0.047、0.007);早期视野损害组合并高度近视的患者比例(9.68%)及有青光眼相关症状的患者比例(29.03%)均小于中晚期视野损害组(29.27%、53.66%),差异均有统计学意义(P=0.029、0.019)。早期视野损害组的性别比例、身体质量指数、家族史、中央角膜厚度与中晚期视野损害组相比,差异均无统计学意义(均为P0.05)。眼压与患者确诊时的视野损害严重程度呈正相关(r=0.411,P=0.000)。结论大多数POAG患者确诊时已发生较严重的视野损害,高眼压、青光眼相关症状、合并高度近视、确诊时年龄偏低可能是POAG患者确诊时发生较严重视野损害的危险因素。
[Abstract]:Objective to analyze the primary open-angle glaucoma (primary open-angle glaucoma, POAG) and the related factors of degree of visual field damage patients. Methods from May 2014 to October 2015 in our hospital 113 POAG patients and 113 eyes. According to visual field damage classification were divided into the early vision damage group (grade 0~1 and visual field damage) advanced vision damage group (field damage 2~5). Sex on the age of diagnosis, two groups of patients, body mass index, glaucoma related symptoms, family history, high myopia, central corneal thickness, intraocular pressure and other related factors were analyzed. Results the vision of the early group (27.43%), 31 eyes of advanced visual field damage group of 82 eyes (72.57%). The age of diagnosis for early vision damage group (52.81 + 16.57), intraocular pressure (23.67 + 11.44) mm Hg (1 kPa=7.5 mmHg), and advanced visual field damage group (45.62 + 17.12) and (30.58 + 12.13) mm Compared to Hg, the differences were statistically significant (P=0.047,0.007); early visual field damage and the proportion of patients with high myopia combined with glaucoma (9.68%) and symptoms related to the proportion of patients (29.03%) were less than in advanced vision damage group (29.27%, 53.66%), the differences were statistically significant (P=0.029,0.019). The sex ratio of early vision damage group family history, body mass index, central corneal thickness and visual field damage in the late group, there were no significant differences (P0.05). The intraocular pressure of patients with visual field damage severity was positively correlated (r=0.411, P=0.000). Conclusion most of the POAG patients have occurred vision damage, serious high intraocular pressure, glaucoma symptoms associated with high myopia, age at diagnosis may be a risk factor for severe low vision damage POAG patients.

【作者单位】：南方医科大学附属武汉临床医学院;广州军区武汉总医院眼科;
【分类号】：R775
【正文快照】： 青光眼是全球不可逆致盲眼病的首要病因[1],预计2040年将会有1亿人患青光眼[2]。青光眼因其发病的隐匿性和视神经损害的不可逆性极具危害。多数基于人群的研究显示原发性开角型青光眼(primary open-angle glaucoma,POAG)是最常见的青光眼类型,老龄、近视、高眼压、青光眼家族

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