噪声性耳聋机制的研究进展

发布时间：2018-02-01 08:49

本文关键词： 噪声性耳聋毛细胞研究进展致病机制　出处：《中华耳科学杂志》2017年03期 　论文类型：期刊论文

【摘要】：噪声性耳聋(Noise-induced Hearing Loss,NIHL)是由于长期暴露在噪声环境下造成渐进性的听力损失或短时间内遭受高强度的爆震或声音刺激导致的感音神经性聋[1]。随着现代社会工业化的高速发展,噪声无时无刻发生在我们身边,影响着我们的听力。如交通噪声、娱乐噪声、工作噪声,已经成为干扰我们生活的社会问题。因此,如何消除或减少噪声以及噪声暴露的防护是当今社会环境保护的工作重点。充分了解噪声所导致的内耳及听神经的损伤机制,代谢性损伤学说,以及对应的防护和治疗方法,为今后对于NIHL的研究奠定实验和理论基础,有助于临床工作中对NIHL的理解并指导治疗方案。
[Abstract]:Noise-induced Hearing Loss. NIHLs are sensorineural deafness due to prolonged exposure to noise resulting in progressive hearing loss or a short period of high intensity detonation or sound stimulation. [With the rapid development of industrialization in modern society, noise occurs all the time, affecting our hearing, such as traffic noise, entertainment noise, work noise. Has become a social problem that interferes with our lives. How to eliminate or reduce the noise and the protection of noise exposure is the focus of the social environmental protection. Fully understand the noise caused by the inner ear and auditory nerve damage mechanism, metabolic damage theory. The corresponding protective and therapeutic methods will lay the experimental and theoretical foundation for the study of NIHL in the future and be helpful to the understanding of NIHL in clinical work and guiding the treatment plan.
【作者单位】：中国医科大学附属盛京医院耳科;
【分类号】：R764.43
【正文快照】： 噪声性耳聋随着社会的发展越来越多的受到人们的重视,随着发病率的逐年增高,也越来越受到国内外研究学者的关注。不同个体对噪声的敏感度存在差异,长时间暴露在噪声环境下都将导致听力受损,85d B以上的噪声具有听力损伤性[2]。研究表明,NIHL首先发生在4k Hz,之后向高频发展,表

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