老年翼状胬肉切除自体角膜缘干细胞移植术后应用软性角膜接触镜的效果

发布时间：2018-02-10 23:58

本文关键词： 软性角膜接触镜翼状胬肉自体角膜缘干细胞移植术　出处：《中国老年学杂志》2017年06期 　论文类型：期刊论文

【摘要】：目的探讨软性角膜接触镜治疗老年翼状胬肉切除自体角膜缘干细胞移植术后的临床疗效及安全性。方法按照随机数字表法将93例原发性老年单侧翼状胬肉患者分为观察组(n=47)和对照组(n=46),两组均行翼状胬肉切除联合自体角膜缘干细胞移植手术,观察组术后佩戴治疗性软性角膜接触镜,对照组术后通过绷带对患眼进行加压包扎。记录两组术后第1、3、5、7天的视觉模拟评分(VAS)、角膜上皮修复时间、术后并发症情况以及随访6个月时的复发率。结果术后第3、5、7天,两组VAS评分均低于术后第1天,且观察组低于对照组(P0.05);观察组角膜上皮修复时间少于对照组,角膜刺激症状发生率低于对照组(均P0.05);随访6个月时,两组翼状胬肉复发率比较无统计学差异(P0.05)。结论软性角膜接触镜能有效减轻老年患者翼状胬肉切除自体角膜缘干细胞移植术后的疼痛,且有利于角膜上皮的恢复,安全性高,预后较好。
[Abstract]:Objective to investigate the clinical efficacy and safety of soft contact lens in the treatment of senile pterygium after limbal stem cell transplantation. Methods 93 cases of primary unilateral pterygium were divided into three groups according to random number table. Pterygium excision combined with limbal stem cell autotransplantation was performed in both groups. The experimental group wore a therapeutic soft contact lens after operation, and the control group used bandage to compress the affected eyes. The visual analogue score (VAS) and corneal epithelium repair time were recorded on the 1st and 3rd and 5th day after operation in both groups. Results the VAS score of the two groups was lower than that of the first day after operation, and that of the observation group was lower than that of the control group (P 0.05), the time of corneal epithelium repair in the observation group was less than that in the control group, the recovery time of corneal epithelium in the observation group was less than that in the control group. The incidence of corneal irritation was lower than that of the control group (all P 0.05). There was no significant difference in the recurrence rate of pterygium between the two groups (P0.050.Conclusion soft corneal contact lens can effectively relieve the pain of limbal stem cell transplantation after pterygium excision, and is beneficial to the recovery of corneal epithelium and is safe. The prognosis is good.
【作者单位】：贵州省人民医院眼科;
【分类号】：R779.6

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