悬雍垂腭咽成形术治疗OSAHS的远期疗效观察

发布时间：2018-02-20 06:35

本文关键词： 阻塞性睡眠呼吸暂停低通气综合征悬雍垂腭咽成形术睡眠疗效生活质量远期效果　出处：《中华全科医学》2016年07期 　论文类型：期刊论文

【摘要】：目的探讨悬雍垂腭咽成形术对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者远期疗效及生活质量的影响,为改善OSAHS患者预后提供临床依据。方法选择南浔区人民医院2010年1月—2013年1月就诊的50例中、重度OSAHS患者作为研究对象,均行悬雍垂腭咽成形术治疗,于术前及术后1、12、24个月时检测患者呼吸暂停通气指数(AHI)、总睡眠时间、最低血氧饱和度(SaO_2)、3+4期睡眠比例、快速动眼睡眠比例和魁北克睡眠问卷(QSQ)测评,于术前及术后24个月时行Epworth嗜睡量表(ESS)测评,并对2组患者的检测结果进行统计学处理。结果在50例患者中共47例完成调查(94.00%);术后24个月,ESS测评结果显著优于术前(Z=2.611,P0.05);术后1、12、24个月时,SaO_2、3+4期睡眠比例、快速动眼睡眠比例均高于术前,AHI均低于术前(P0.05);术后12、24个月时,SaO_2、3+4期睡眠比例、快速动眼睡眠比例均高于术后1个月,AHI均低于术后1个月(P0.05);术后1、12、24个月时,QSQ各维度评分及总分均高于术前(P0.05);术后12、24个月时,QSQ各维度评分及总分均高于术后1个月(P0.05);术后12、24个月时,QSQ各维度评分及总分比较差异无统计学意义(P0.05)。结论悬雍垂腭咽成形术能够显著改善中、重度OSAHS患者的远期睡眠疗效及生活质量,明显减轻了患者嗜睡程度,值得临床重视。
[Abstract]:Objective to investigate the effect of uvulopalatopharyngoplasty on the long-term efficacy and quality of life in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods in order to improve the prognosis of patients with OSAHS, 50 patients with severe OSAHS were selected from Nanxun people's Hospital from January 2010 to January 2013. All patients were treated with uvulopalatopharyngoplasty. Apnea index (AHI), total sleep time, minimum blood oxygen saturation (SAO), sleep rate of stage 34, rapid eye movement (REM) sleep ratio and Quebec sleep questionnaire (QSQs) were measured before and after operation of 12 and 24 months. Epworth somnolence scale (Epworth) was used before and 24 months after operation. Results in 50 patients, 47 patients completed the investigation, and 24 months after operation, the results of ESS test were significantly better than that of pre-operation, 112m, 24 months after operation, and 24 months after operation, the sleep ratio of SaO2S stage 3 to 4 was significantly higher than that of pre-operation. The ratio of rapid eye movement sleep was higher than that of preoperative AHI, and the sleep ratio of Sao at 12 and 24 months after operation was lower than that of preoperation (P 0.05), and that of Sao at 12 and 24 months after operation was higher than that of preoperative AHI. The ratio of rapid eye movement sleep was higher than that of 1 month after operation (P 0.05), the scores and total scores of QSQ at 112 and 24 months after operation were higher than those before operation (P 0.05), and the scores and total scores of QSQ at 12 and 24 months after operation were higher than those at 1 month after operation. There was no significant difference in the scores and total scores of QSQ between 12 and 24 months after operation. Conclusion Uvulopalatopharyngoplasty can improve significantly. The long-term sleep effect and quality of life of patients with severe OSAHS have significantly reduced the degree of somnolence and deserve clinical attention.
【作者单位】：湖州市南浔区人民医院五官科;浙江大学湖州医院呼吸内科;
【基金】：2014年浙江省卫计委平台骨干人才项目(2014-RCA-029)
【分类号】：R766.9

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