阻塞性睡眠呼吸暂停低通气综合征患者不同刺激率ABR结果分析

发布时间：2018-02-21 04:48

  本文关键词： 睡眠呼吸暂停低通气综合征 高刺激率 听性脑干反应　出处：《听力学及言语疾病杂志》2016年04期 　论文类型：期刊论文

【摘要】：目的探讨高刺激率ABR对阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)患者听力评估的价值及其与低氧血症的相关性。方法对39例(78耳)OSAHS患者(中度5例、重度34例)和34例(68耳)正常成年人分别进行11.1、31.1、51.1次"秒刺激率的听性脑干反应(ABR)测试,比较组间结果,并与多导睡眠监测呼吸暂停低通气指数(AHI)、最低血氧饱和度(LSaO2)、平均血氧饱和度(MSaO2)、氧饱和度≤90%的时间占总监测时间的百分比(SIT90)、氧饱和度≤80%的时间占总监测时间的百分比(SIT80)进行相关性分析。结果在11.1次"秒刺激率时OSAHS组ABR波Ⅴ潜伏期(5.79±0.22ms)较对照组(5.67±0.24ms)延长;31.1次"秒刺激率时OSAHS组ABR波Ⅰ潜伏期(1.85±0.18ms)、波Ⅴ潜伏期(5.98±0.19ms)均较对照组(分别为1.76±0.16ms、5.82±0.24ms)延长;在51.1次"秒刺激率时OSAHS组ABR波Ⅰ潜伏期(1.94±0.26ms)、波Ⅴ潜伏期(6.09±0.25ms)较对照组(分别为1.83±0.15ms、5.99±0.24ms)延长。刺激率由11.1次"秒升高至31.1次"秒时,OSAHS组波Ⅰ潜伏期延长,ΔⅠ_(31.1-11.1)(0.12±0.17ms)较对照组(0.07±0.11ms)长,刺激率由11.1次"秒升高至51.1次"秒时,OSAHS组波Ⅰ潜伏期延长,ΔⅠ51.1-11.1(0.21±0.25ms)较对照组(0.15±0.10ms)长。ΔⅠ_(31.1-11.1)与LSaO2负相关(r=-0.24),与SIT90(r=0.23)、SIT80(r=0.27)正相关;ΔⅠ51.1-11.1与LSaO2(r=-0.33)、MSaO2(r=-0.35)负相关,与SIT90(r=0.37)、SIT80(r=0.29)正相关;以上差异及相关性均有统计学意义(p0.05)。结论高刺激率ABR可发现中度及重度OSAHS患者耳蜗及听神经近耳蜗段的损伤。
[Abstract]:Objective to investigate the value of high stimulation rate ABR in hearing evaluation of patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) and its correlation with hypoxemia. Methods 39 cases (5 moderate cases) of OSAHS with 78 ears of obstructive sleep apnea hypopnea syndrome (OSAHS) were studied. The auditory brainstem response (ABR) test was performed in 34 severe cases (n = 34) and 34 normal adults (n = 34). The results of ABR were compared between the two groups, and the auditory brainstem response (ABR) was measured at the rate of 51.1 "second stimuli". With polysomnography, apnea hypopnea index (apnea hypopnea index), minimum oxygen saturation (LSAO _ 2), mean oxygen saturation (MSaO _ 2), oxygen saturation 鈮，

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