急性脑卒中合并不同程度阻塞性睡眠呼吸暂停低通气综合征患者伴发脑心综合征的临床分析

发布时间：2018-02-24 20:39

本文关键词： 脑卒中睡眠呼吸暂停阻塞性脑心综合征　出处：《中国临床保健杂志》2016年06期 　论文类型：期刊论文

【摘要】：目的探讨急性脑卒中合并不同程度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者发生脑心综合征(CCS)的差异性,为临床监测及干预治疗提供依据。方法收集急性脑卒中合并OSAHS患者471例,其中缺血性卒中伴轻度OSAHS组85例,缺血性卒中伴中度OSAHS组74例,缺血性卒中伴重度OSAHS组68例,出血性卒中伴轻度OSAHS组69例,出血性卒中伴中度OSAHS组83例,出血性卒中伴重度OSAHS组92例。观察各组心电图、心肌酶、肌钙蛋白的变化。结果缺血性脑卒中合并不同程度OSAHS患者发生CCS的比较,差异有统计学意义(χ~2=6.532,P=0.012),其中两两比较差异均有统计学意义(P0.01)。出血性脑卒中合并不同程度OSAHS患者发生CCS的比较,差异有统计学意义(χ~2=12.741,P=0.005),其中两两比较差异均有统计学意义(P0.01)。缺血性卒中合并轻度OSAHS与出血性卒中合并轻度OSAHS患者发生CCS的比较,差异有统计学意义(χ~2=6.972,P=0.010)。缺血性卒中合并中度OSAHS与出血性卒中合并中度OSAHS患者发生CCS的比较,差异有统计学意义(χ~2=9.248,P=0.005)。缺血性卒中合并重度OSAHS与出血性卒中合并重度OSAHS患者发生CCS的比较,差异有统计学意义(χ~2=10.831,P=0.005)。结论急性脑卒中合并OSAHS的患者,随着OSAHS程度的加重,CCS的发生率增加,且出血性卒中合并OSAHS的患者较缺血性卒中合并OSAHS的患者更易导致CCS的发生。
[Abstract]:Objective to investigate the difference of CCSs in patients with acute stroke complicated with obstructive sleep apnea hypopnea syndrome (OSAHS). Methods 471 patients with acute cerebral apoplexy complicated with OSAHS were collected, including 85 cases of ischemic stroke with mild OSAHS, 74 cases of ischemic stroke with moderate OSAHS and 68 cases of ischemic stroke with severe OSAHS. There were 69 cases of hemorrhagic stroke with mild OSAHS, 83 cases of hemorrhagic stroke with moderate OSAHS, 92 cases of hemorrhagic stroke with severe OSAHS. Results the changes of cardiac troponin in patients with ischemic stroke complicated with different degrees of OSAHS were compared. The difference was statistically significant (蠂 ~ (2 +) 6.532) (P = 0.012), in which there was a significant difference between two groups (P < 0.01). The incidence of CCS in patients with hemorrhagic stroke complicated with different degrees of OSAHS was compared. The difference was statistically significant (蠂 ~ (2 +) P ~ (12.741) P ~ (0.005)), in which there was significant difference between two groups (P < 0.01). The CCS in patients with ischemic stroke complicated with mild OSAHS and hemorrhagic apoplexy with mild OSAHS was significantly higher than that in patients with hemorrhagic stroke and mild OSAHS. The difference was statistically significant (蠂 ~ (2 / 2) 6.972). The incidence of CCS in patients with ischemic stroke with moderate OSAHS and hemorrhagic stroke with moderate OSAHS was higher than that with hemorrhagic stroke. The difference was statistically significant (蠂 ~ 2 / 2 / 9.248 / P ~ (0.005)). There was a significant difference in the incidence of CCS in patients with ischemic stroke with severe OSAHS and hemorrhagic apoplexy with severe OSAHS (蠂 ~ (2 +)) (蠂 ~ (2 / 2) = 10.831). Conclusion there is a significant difference in the incidence of CCS in patients with acute cerebral apoplexy complicated with OSAHS. With the exacerbation of OSAHS, the incidence of OSAHS increased, and hemorrhagic stroke patients with OSAHS were more likely to lead to CCS than ischemic stroke patients with OSAHS.
【作者单位】：新疆维吾尔自治区人民医院北院急诊病房;
【分类号】：R743.3;R766

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