鼠神经生长因子治疗后天麻痹性斜视疗效观察

发布时间：2018-03-04 15:12

本文选题：后天麻痹性斜视　切入点：神经生长因子类　出处：《中国现代医学杂志》2017年13期 　论文类型：期刊论文

【摘要】：目的观察鼠神经生长因子治疗后天麻痹性斜视的临床疗效。方法将82例后天麻痹性斜视患者随机分为鼠神经生长因子治疗组(治疗组)41例和常规治疗组(对照组)41例。对照组甲钴胺片口服0.5 mg,3次/d,维生素B1口服10 mg,3次/d,治疗组加用肌肉注射鼠神经生长因子18μg,1次/d,14 d为1个疗程,治疗3个疗程后观察疗效。结果痊愈26例(63.41%),有效10例(24.39%),无效5例(12.20%),总有效率87.80%;对照组痊愈13眼(31.71%),有效17眼(41.46%),无效11眼(26.83%),总有效率73.17%,两组疗效差异有统计学意义(Z=-2.807,P0.05),且治疗组三棱镜斜视度改善程度优于对照组,差异有统计学意义(P0.05)。结论鼠神经生长因子治疗后天麻痹性斜视能提高临床疗效,改善症状,减轻斜视度,值得推广。
[Abstract]:Objective to observe the clinical efficacy of nerve growth factor (NGF) in the treatment of postnatal paralytic strabismus. Methods 82 cases of acquired paralytic strabismus were randomly divided into treatment group (n = 41) and routine treatment group (n = 41). The control group received 0.5 mg / d oral dose of 0.5 mg / d and vitamin B1 10 mg / d for 3 times / d. The treatment group received intramuscular injection of nerve growth factor 18 渭 g / d for 14 days as a course of treatment. Results after 3 courses of treatment, the curative effect was observed in 26 cases (63.41), effective in 10 cases (24.39) and ineffective in 5 cases (12.20), the total effective rate was 87.80; in the control group, 13 eyes were cured and 31.71%, 17 eyes were effective 41.46D, 11 eyes were ineffective and the total effective rate was 73.17. The difference between the two groups was statistically significant. The degree of improvement of prism strabismus in the treatment group was better than that in the control group. Conclusion the treatment of postnatal paralytic strabismus in rats with nerve growth factor can improve the clinical effect, improve the symptoms and reduce the degree of strabismus, which is worth popularizing.
【作者单位】：天津中医药大学第一附属医院;
【分类号】：R777.4

【相似文献】