FESS联合MMT对中-重度CRSsNP的疗效及对鼻腔黏液纤毛清除能力的影响

发布时间：2018-03-07 17:55

  本文选题：功能性内镜鼻旁窦手术　切入点：加强药物治疗　出处：《现代医学》2016年11期 　论文类型：期刊论文

【摘要】：目的:探讨功能性内镜鼻旁窦手术(FESS)联合加强药物治疗(MMT)对中-重度慢性鼻-鼻旁窦炎不伴鼻息肉(CRSsNP)的疗效及对鼻腔黏液纤毛清除能力的影响。方法:选取我院治疗的CRSsNP患者120例为研究对象,按照随机数字表法分为研究组与对照组各60例,对照组予MMT治疗,研究组在对照组基础上予FESS治疗,比较两组患者的疗效和鼻腔黏液纤毛清除能力。结果:研究组患者的总有效率显著高于对照组(P0.05)。治疗后4及8周,两组患者的糖精清除时间呈降低趋势,研究组显著低于对照组(P0.05),而两组患者的黏液纤毛清除速度及腔黏液纤毛清除率呈上升趋势,研究组显著高于对照组(P0.05)。结论:FESS联合MMT对中-重度CRSsNP具有较好的临床疗效,能够显著提高患者鼻腔黏液纤毛清除能力,值得临床推广。
[Abstract]:Objective: to investigate the effect of functional endoscopic parasasal sinus surgery (FESS) combined with enhanced drug therapy (MMTT) on moderate to severe chronic rhino-paranasal sinusitis without CRSsNPs and its effect on mucociliary clearance of nasal cavity in our hospital. One hundred and twenty patients with CRSsNP were studied. According to the method of random number table, the study group was divided into two groups, 60 cases in the study group and 60 cases in the control group. The control group was treated with MMT and the study group was treated with FESS on the basis of. Results: the total effective rate of the patients in the study group was significantly higher than that in the control group (P 0.05). The clearance time of saccharin in the two groups decreased 4 and 8 weeks after treatment. The mucociliary clearance rate and cavity mucociliary clearance rate in the two groups were significantly higher than those in the control group (P 0.05). Conclusion the combination of MMT and Fess has a better clinical effect on moderate to severe CRSsNP. It can significantly improve the mucociliary clearance ability of the nasal cavity of the patients, and is worthy of clinical promotion.
【作者单位】： 泗洪县人民医院耳鼻咽喉科;
【分类号】：R765.9
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本文编号：1580341