典型中耳病变对圆窗激振听力补偿性能影响的数值分析

发布时间：2018-03-14 20:43

本文选题：中耳病变　切入点：圆窗激振　出处：《医用生物力学》2017年04期 　论文类型：期刊论文

【摘要】：目的研究典型中耳病变对圆窗激振听力补偿效果的影响,为圆窗激振式人工中耳的优化设计提供参考。方法利用CT扫描和逆向成型技术建立包括中耳和耳蜗的有限元模型,并验证模型的可靠性。再基于该模型,通过改变相应组织的材料属性,分别模拟镫骨环韧带硬化、镫骨不正常发育和锤骨前韧带硬化3种典型中耳病变。通过对比相应的基底膜响应,分析这3种病变对圆窗激振听力补偿效果的影响。结果镫骨不正常发育主要在高频处降低圆窗激振的效果,镫骨环韧带硬化和锤骨前韧带硬化主要恶化圆窗激振低频段的响应。3种病变中,镫骨环韧带硬化对圆窗激振听力补偿效果影响较大,等效声压的减小量可高达17 d B。结论中耳病变恶化圆窗激振的听力补偿效果,且恶化量较大,故在设计圆窗激振式人工中耳时需要针对性地提高其作动器的输出量。
[Abstract]:Objective to study the effect of typical middle ear disease on hearing compensation of round window induced hearing. Methods the finite element model including middle ear and cochlea was established by CT scanning and reverse molding. And verify the reliability of the model. Based on the model, by changing the material properties of the corresponding tissue, respectively, the sclerosis of the ligamentum annulus stapes was simulated. The abnormal development of stapes and the sclerosis of anterior ligament of malleus were three kinds of typical middle ear diseases. The effects of these three lesions on hearing compensation of round window induced vibration were analyzed. Results the abnormal development of stapes mainly reduced the effect of round window excitation at high frequency. Among the three kinds of pathological changes, the sclerosis of the annular ligament of the stapes and the anterior ligament of the malleus mainly worsen the response of the low frequency band excited by round window, and the effect of the sclerosis of the annular ligament of the stapes on the hearing compensation caused by the round window is great. The equivalent sound pressure can be reduced to up to 17 dB. Conclusion the hearing compensation effect of circular window excitation is aggravated by the lesion of middle ear, and the deterioration is large. Therefore, it is necessary to improve the output of actuator in designing round window induced artificial middle ear.
【作者单位】：中国矿业大学机电工程学院;上海交通大学机械系统与振动国家重点实验室;
【基金】：国家自然科学基金项目(51305442) 江苏省自然科学基金项目(BK20130194) 高等学校博士学科点专项科研基金项目(20130095120010)
【分类号】：R764

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