阻塞性睡眠呼吸暂停低通气综合征儿童术后的认知功能恢复的探讨

发布时间：2018-03-18 12:19

本文选题：阻塞性睡眠呼吸暂停低通气综合征　切入点：认知功能　出处：《宁夏医科大学》2012年硕士论文　论文类型：学位论文

【摘要】：目的探讨扁桃体和（或）腺样体切除术后，对阻塞性睡眠呼吸暂停低通气综合征儿童认知功能的影响。方法术前对65名OSAHS患儿采用多导睡眠监测和认知功能检查（包括中国修订版韦氏儿童智力量表、中国修订版韦氏幼儿智力量表、注意力测试），在术后6个月进行相关随访，并与健康同龄儿童正常值比较，，数据采用SPSS11.5统计软件进行分析。结果①在韦氏幼儿智力量表的大部分项目上，学龄前期OSAHS患儿术后结果高于术前组，和健康儿童相比，仅在知识、画图填充分测验中，有统计学意义；在言语智商、操作智商、总智商较术前均有提高，而和正常组相比三者均没有统计学意义。②学龄组患儿术后和术前比较，在韦氏儿童智力量表的大部分项目上有显著差异性，在知识、填图数据上，术后OSAHS儿童的结果较正常组低；在言语智商、操作智商、总智商较术前均有显著提高，同正常组比较无统计学意义；注意力测试结果术后患儿高于术前，而与正常儿童比较无统计学差异性。结论阻塞性睡眠呼吸暂停低通气综合征，造成儿童认知功能损害，在手术治疗后大部分认知功能可以恢复近正常，提示大部分受损的认知功能是可以逆转的，因此需尽早进行手术干预。
[Abstract]:Objective to investigate the effects of tonsillectomy and / or adenoidectomy on cognitive function in children with obstructive sleep apnea hypopnea syndrome (OSAS). Methods Sixty-five children with OSAHS were examined with polysomnography and cognitive function (including China revised Wechsler Intelligence scale, Chinese revised Wechsler Intelligence scale and attention test), and were followed up 6 months after operation. Compared with the normal values of healthy children of the same age, the data were analyzed by SPSS11.5 software. Results (1) in most items of Wechsler Infant Intelligence scale, the postoperative results of pre-school children with OSAHS were higher than those of the preoperative group. Compared with the healthy children, there was statistical significance only in the knowledge and drawing filling subtest, and in the verbal intelligence quotient. Compared with the normal group, the three groups had no statistical significance. 2. There were significant differences in most items of Wechsler Children's Intelligence scale, and there were significant differences in the knowledge among the three groups, and there was no significant difference between the three groups before and after operation. In the mapping data, the results of postoperative OSAHS children were lower than those of the normal group, the verbal intelligence quotient, the operational intelligence quotient and the total intelligence quotient were significantly higher than those before the operation, but there was no statistical significance compared with the normal group, and the attention test results were higher than those before the operation. There was no statistical difference between children and normal children. Conclusion obstructive sleep apnea hypopnea syndrome can cause cognitive impairment in children. Most of the cognitive function can be restored to normal after operation, suggesting that most of the impaired cognitive function can be reversed. Therefore, surgical intervention should be carried out as soon as possible.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R766

【参考文献】