泪道探通与妥布霉素地塞米松眼膏联合治疗泪道阻塞的临床疗效

发布时间：2018-03-18 14:02

本文选题：泪道阻塞　切入点：泪道探通术　出处：《中国医学工程》2016年11期 　论文类型：期刊论文

【摘要】：目的研究泪道探通与妥布霉素地塞米松眼膏联合治疗泪道阻塞的临床效果。方法选取该院2014年1月-2015年6月接收的78例(95眼)泪道阻塞患者为研究对象,采用随机数字表法分为两组。对照组39例(48眼)单纯给予泪道探通术治疗;观察组39例(47眼)给予泪道探通与妥布霉素地塞米松眼膏联合治疗。比较两组治疗总有效率、复发率及不良反应发生率。结果观察组治疗总有效率为95.7%(45/47),对照组为79.2%(38/48),观察组高于对照组,差异有统计学意义(X~2=5.914,P=0.015)。观察组不良反应发生率为10.6%(5/47),对照组为6.3%(3/48),观察组高于对照组,但差异无统计学意义(X~2=0.593,P=0.345)。随访6~18个月,观察组复发率为12.8%(6/47),对照组为31.3%(15/48),观察组低于对照组,差异有统计学意义(X~2=4.712,P=0.026)。结论泪道探通与妥布霉素地塞米松眼膏联合治疗泪道阻塞疗效确切,安全性高,值得临床上推广应用。
[Abstract]:Objective to study the clinical effect of lacrimal duct exploration combined with tobramycin dexamethasone eye ointment in the treatment of lacrimal duct obstruction. The control group (39 cases, 48 eyes) was treated with lacrimal passage exploration, while the observation group, 39 cases (47 eyes) with lacrimal duct exploration and tobramycin dexamethasone eye ointment, were divided into two groups. The total effective rate of the two groups was compared. Results the total effective rate of treatment was 95.775 / 47 in the observation group and 79.2 / 48 in the control group. The observation group was higher than the control group, and the difference was statistically significant. The incidence of adverse reactions in the observation group was 10.6 / 5 / 47, and in the control group was 6.33.48%, which was higher than that in the control group. But the difference was not statistically significant. Follow-up for 6 ~ 18 months showed that the recurrence rate of the observation group was 12.80.47%, and that of the control group was 31.3%. The difference between the observation group and the control group was statistically significant, and the difference was statistically significant. Conclusion the lacrimal passage exploration combined with tobramycin dexamethasone ophthalmic ointment is effective in the treatment of lacrimal duct obstruction. It is safe and worth popularizing in clinic.
【作者单位】：广东省深圳市龙岗区第六人民医院五官科(眼科);
【分类号】：R777.2

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