阻塞性睡眠呼吸暂停低通气综合征患者自然睡眠时上气道及相关结构电影磁共振测量研究

发布时间：2018-04-01 18:03

本文选题：睡眠呼吸暂停　切入点：阻塞性　出处：《中国耳鼻咽喉头颈外科》2016年04期

【摘要】：目的采用电影磁共振(cine magnetic resonance,CMR)定量评估不同上气道阻塞模式下阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的上气道及其相关结构的变化特点。方法 30例男性重度OSAHS患者成功完成清醒时和自然睡眠时上气道正中矢状位CMR扫描。根据上气道阻塞模式将患者分为三组,并对患者的上气道及相关结构进行测量,评估其形态及位置变化特点。结果与清醒时相比,自然睡眠时OSAHS患者软腭后区、舌后区和会厌后区上气道矢状径均明显减小,硬腭-软腭间夹角增大,舌骨上肌群长度减小(P0.01)。三型阻塞模式患者在清醒时,舌后区上气道矢状径存在显著差异(P0.01);自然睡眠时,舌后区上气道矢状径、舌体上部矢状径、硬腭-软腭间夹角、舌体角及上述测量指标的变化值均有显著差异(P0.05)。结论 CMR可定量评估不同上气道阻塞模式的OSAHS患者之间上气道及相关结构的变化特点。
[Abstract]:Objective to quantitatively evaluate the changes of upper airway and its related structures in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) under different upper airway obstruction patterns using cine magnetic resonance imaging. Methods 30 cases of male patients with severe OSAHS were studied. The patients successfully completed CMR scans of the upper airway on the median sagittal position during waking and natural sleep. The patients were divided into three groups according to the pattern of upper airway obstruction. The changes of the upper airway and its related structures were evaluated. Results the sagittal diameters of the upper airway of OSAHS patients during natural sleep were significantly reduced compared with those of normal sleep, and the sagittal diameter of the upper airway in the posterior region of tongue and posterior epiglottis was significantly decreased in the patients with OSAHS. The angle between hard palate and soft palate increased and the length of superior hyoid muscle group decreased (P 0.01). There was a significant difference in the sagittal diameter of the upper airway in the posterior lingual region in patients with type 3 occlusion when they were awake, and the sagittal diameter of the upper airway in the posterior part of the tongue and the superior sagittal diameter of the upper part of the tongue during natural sleep, and the sagittal diameter of the upper part of the tongue during natural sleep. There were significant differences in the angle between the hard palate and soft palate, the angle of the body of tongue and the changes of the above indexes. Conclusion CMR can quantitatively evaluate the changes of the upper airway and related structures among the patients with different upper airway obstruction patterns.
【作者单位】：首都医科大学附属北京同仁医院放射科;北京清华长庚医院耳鼻咽喉头颈外科;首都医科大学临床生物力学应用基础研究北京市重点实验室;
【基金】：中国博士后科学基金面上资助项目(2011M500026) 北京市卫生系统高层次卫生技术人才学科带头人项目(20142005)联合资助
【分类号】：R766;R445.2

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