干眼危险因素的研究

发布时间：2018-04-03 08:51

  本文选题：干眼　切入点：睑板腺功能障碍　出处：《眼科新进展》2017年12期

【摘要】：目的探讨干眼的危险因素及发生频率。方法 564例(564眼)纳入研究,采用问卷调查的方式对研究对象干眼的症状、体征及全身情况进行评估。采用SPSS 16.0统计学软件分析数据,χ2和t检验进行组间差异分析,Logistic回归分析危险因素和干眼的关系。结果口干与重症干眼的症状(OR=2.89,95%CI:1.6~5.5,P=0.001)有相关性。使用胃溃疡药物加重重症干眼的症状(OR=2.60,95%CI:1.1~5.1,P=0.04)。使用人工泪液加重重症干眼体征(OR=2.1,95%CI:1.2~3.2,P=0.01)。口干(OR=1.92,95%CI:1.02~3.60,P=0.04)及使用利尿剂(OR=6.00,95%CI:1.3~41.0,P=0.02)均为泪液分泌障碍的危险因素。年龄较大(OR=1.02,95%CI:1.05~1.09,P=0.000)、男性(OR=1.42,95%CI:1.04~2.60,P=0.02)、关节炎(OR=8.00,95%CI:1.0~59.0,P=0.02)和使用降压药(OR=2.85,95%CI:1.3~5.7,P=0.01)为睑板腺功能障碍的危险因素。口干是角膜染色的危险因素(OR=2.21,95%CI:1.1-5.4,P=0.02)。结论不同的危险因素对干眼影响不同,表明干眼的不同亚型具有不同病理生理机制。
[Abstract]:Objective to investigate the risk factors and frequency of dry eye.Methods 564 cases (564 eyes) were included in the study. The symptoms, signs and systemic conditions of dry eyes were evaluated by questionnaire.SPSS 16.0 statistical software was used to analyze the data, 蠂 2 and t test were used to analyze the relationship between the risk factors and dry eyes by logistic regression analysis.Results there was a correlation between dry mouth and the symptoms of severe dry eye.The symptoms of severe dry eye were aggravated by gastric ulcer drugs.Artificial tear was used to aggravate the severe dry eye signs.The risk factors of tear secretion disorder were: I: 1.023.60P0.04) and the use of diuretics: 6.000.95 CI: 1.92P0.02).骞撮緞杈冨ぇ(OR=1.02,95%CI:1.05~1.09,P=0.000),鐢锋，

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