鼻部神经鞘瘤的临床特征及其预后分析

发布时间：2018-04-05 01:10

  本文选题：鼻肿瘤　切入点：神经鞘瘤　出处：《临床耳鼻咽喉头颈外科杂志》2017年24期

【摘要】：目的:探讨鼻部神经鞘瘤的诊治经验,以期对该疾病的诊断及治疗提供指导。方法:对9例鼻部神经鞘瘤患者的临床表现、病理及免疫组织化学特征、手术及预后情况进行分析。结果:9例患者多因压迫或占位症状就诊,影像学检查多无特异性。除1例多发性神经鞘瘤患者拒绝治疗外,余均采取手术治疗,且术后极少复发。病理诊断以S-100蛋白表达强阳性为特点。结论:鼻部神经鞘瘤的临床表现无特异性;影像学对于手术范围及肿瘤的良恶性有指导意义;确诊依靠常规病理及免疫组织化学;手术是唯一有效的治疗方法,手术的选择主要取决于病灶部位,预后佳。
[Abstract]:Objective: to explore the experience of diagnosis and treatment of nasal neurilemmoma and to provide guidance for the diagnosis and treatment of the disease.Methods: the clinical manifestations, pathological and immunohistochemical features, operation and prognosis of 9 patients with nasal neurilemmoma were analyzed.Results 9 cases were treated with compression or space occupying symptoms, and the imaging examination was not specific.With the exception of one patient with polyneurinoma who refused treatment, all patients received surgical treatment and rarely recurred after operation.The pathological diagnosis was characterized by strong positive expression of S-100 protein.Conclusion: the clinical manifestations of nasal neurilemmoma are not specific, the imaging is of guiding significance for the range of operation and the benign and malignant tumor, the diagnosis depends on routine pathology and immunohistochemistry, and surgery is the only effective treatment.The choice of operation mainly depends on the location of the lesion and the prognosis is good.
【作者单位】： 南方医科大学珠江医院(第二临床医学院)耳鼻咽喉头颈外科;
【分类号】：R739.62
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本文编号：1712523