鼻渊通窍颗粒联合孟鲁司特钠咀嚼片治疗儿童过敏性鼻炎

发布时间：2018-04-05 06:35

本文选题：儿童过敏性鼻炎　切入点：孟鲁司特钠咀嚼片　出处：《长春中医药大学学报》2016年05期

【摘要】：目的观察鼻渊通窍颗粒联合孟鲁司特钠咀嚼片治疗儿童过敏性鼻炎的临床疗效及安全性。方法前瞻性选取160例耳鼻喉科2013年1月—2015年1月期间确诊为儿童过敏性鼻炎患儿,投掷硬币法将其分为2组,对照组单纯给予孟鲁司特钠咀嚼片治疗,治疗组在此基础上加用鼻渊通窍颗粒,观察2组临床症状和体征改善情况,评估临床疗效及安全性。结果 2组治疗后喷嚏、流涕、鼻痒、鼻塞、局部体征评分均较治疗前明显降低(P0.05),疗程结束时治疗组各项评分均明显低于对照组(P0.05);治疗组痊愈率、显效率和总有效率明显高于对照组(P0.05),均未发生明显不良反应。结论鼻渊通窍颗粒联合孟鲁司特钠咀嚼片可明显改善儿童过敏性鼻炎的临床症状和体征,疗效显著,未见明显不良反应。
[Abstract]:Objective to observe the efficacy and safety of Biyuan Tongqiao granule combined with montelukast sodium chewable tablet in the treatment of allergic rhinitis in children.Methods 160 children with allergic rhinitis from January 2013 to January 2015 in otolaryngology were prospectively selected and divided into two groups by coin throwing. The control group was treated with montelukast sodium chewable tablets.In the treatment group, Biyuan Tongqiao granules were added to the treatment group to observe the improvement of clinical symptoms and signs, and to evaluate the clinical efficacy and safety.Results after treatment, the scores of sneezing, runny nose, itchy nose, nasal congestion and local signs in both groups were significantly lower than those before treatment, and at the end of the course of treatment, the scores in the treatment group were significantly lower than those in the control group, and the cure rate in the treatment group was significantly lower than that in the control group.The effective rate and the total effective rate were significantly higher than that of the control group (P 0.05), and no significant adverse reactions occurred.Conclusion Biyuan Tongqiao granule combined with montelukast sodium chewable tablet can obviously improve the clinical symptoms and signs of allergic rhinitis in children.
【作者单位】：广州市番禺区中心医院耳鼻喉科;
【基金】：广州市卫生局科研项目(20141A010102)
【分类号】：R765.21

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