妊娠期并发高血压及高血糖疾病与早产儿视网膜病变的相关性研究

发布时间：2018-04-09 09:02

本文选题：妊娠期高血压　切入点：妊娠期高血糖　出处：《眼科新进展》2016年08期

【摘要】：目的探讨妊娠期并发高血压及(或)高血糖与早产儿视网膜病变的关系。方法回顾分析我院2014年3月至2015年2月早产儿或低出生体质量儿早产儿视网膜病变筛查情况及其孕母临床资料。对妊娠期高血压及妊娠期高血糖与早产儿视网膜病变发病的相关性进行分析。结果收集451例早产儿或低出生体质量儿中早产儿视网膜病变患儿53例(11.75%),患病组与非患病组出生体质量、吸氧史、孕母年龄、孕母高血压及高血糖患病情况差异均有统计学意义(均为P0.05)。早产儿视网膜病变与孕母患高血压情况呈正相关关系(rs=0.390,P0.01),与孕母患高血糖情况亦正相关(rs=0.284,P0.01)。妊娠期高血糖发生相对于妊娠期高血压的相对危险度Rr=2.03;妊娠期高血压发生相对于妊娠期血糖异常的相对危险度Rr=1.55。妊娠期高血压的发生与妊娠期高血糖疾病的发生亦具有相关性(χ~2=24.37,P0.01)。结论妊娠期高血压与妊娠期高血糖与早产儿视网膜病变的发生相关,且妊娠期高血压与妊娠期高血糖的发病具有相关性。
[Abstract]:Objective to investigate the relationship between hypertension and / or hyperglycemia in pregnancy and retinopathy of preterm infants.Methods Retinopathy screening of premature or low birth weight infants in our hospital from March 2014 to February 2015 was retrospectively analyzed.The relationship between hypertension complicating pregnancy and gestational hyperglycemia and retinopathy of preterm infants was analyzed.Results 53 cases of retinopathy of 451 premature or low birth weight infants with retinopathy were collected.There were significant differences in maternal hypertension and hyperglycemia (P 0.05).There was a positive correlation between retinopathy in preterm infants and hypertension in pregnant mothers. There was also a positive correlation between retinopathy and hyperglycemia in pregnant mothers.The relative risk of gestational hyperglycemia relative to pregnancy-induced hypertension is 2.03, and the relative risk of gestational hypertension is 1.55 compared with gestational hyperglycemia.The incidence of hypertension complicating pregnancy was also correlated with the incidence of hyperglycemia in pregnancy (蠂 ~ 2 = 24.37 / P 0.01).Conclusion Hypertension complicating pregnancy is associated with retinopathy of preterm infants, and hypertension complicating pregnancy is associated with the pathogenesis of hyperglycemia in pregnancy.
【作者单位】：陕西省人民医院眼科;解放军四○一医院崂山分院眼科;
【分类号】：R714.2;R774.1

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