数值模拟鼻中隔偏曲伴棘突对鼻腔气流的影响

发布时间：2018-04-09 18:39

本文选题：鼻中隔偏曲　切入点：数值模拟　出处：《青岛大学》2012年硕士论文

【摘要】：目的：利用鼻中隔偏曲患者鼻腔的CT扫描数据建立鼻腔的CFD模型,并通过数值模拟的鼻腔流场进行分析,观察鼻中隔棘突对气流的影响,判断与鼻塞症状的关系。方法：36例鼻中隔偏曲棘突患者采用视觉模拟量表评分(VAS)评价鼻塞症状严重程度。应用16排螺旋CT对36例鼻中隔偏曲棘突型患者及30例正常人进行鼻部的连续薄层扫描。应用医学图象重建软件Mimics导入CT扫描数据建立鼻腔三维模型,再转换为CFD模型。通过计算机流体力学软件Fluent设置在潮气量400ml的条件下进行模拟及再现鼻腔气流流动。结果：36例鼻中隔偏曲棘突患者,VAS评分为7(6-8)。经过Fluent模拟潮气量在400ml流量下鼻中隔棘突处吸气及呼气相峰流速分别为8.1±1.52m/s,-6.7±0.45m/s.棘突附近压强降变化明显,吸气时棘突前方压强升高,棘突后方出现压强减低区域,呼气时相反。VAS评分与吸气及呼气相峰流速及鼻中隔棘突周围气流速度及压强,棘突距前鼻棘距离等因素进行Spearman等级相关性分析。VAS与上述指标无明显相关性。结论：36例鼻中隔偏曲患者及30例正常人鼻腔的CFD模型顺利建立。鼻中隔棘突患者呼吸气流分布与正常人不同,棘突阻碍正常气流流动,改变棘突附近流量分布,对鼻腔内部压强分布产生影响,但流速、压力的改变与鼻塞症状无明显相关性。
[Abstract]:Objective: to establish the CFD model of nasal cavity with CT scanning data of nasal septum deviation, and to observe the influence of spinous process of nasal septum on airflow and to judge the relationship between nasal obstruction and nasal obstruction by numerical simulation of nasal cavity flow field.Methods 36 patients with septum deviation and spinous process were evaluated by visual analogue scale (VASs).Continuous thin slice scan of nasal region was performed in 36 patients with septal deviation and spinous process and 30 normal subjects by 16-slice spiral CT.Medical image reconstruction software Mimics was used to import CT scanning data to establish a three-dimensional model of nasal cavity, and then converted to CFD model.The simulation and reappearance of nasal air flow were carried out by computer fluid dynamics software Fluent under the condition of tidal volume 400ml.Results the VAS score of 36 patients with septum deviation and spinous process was 76-8.The peak flow rate of inspiratory and expiratory phase at the spinous process of nasal septum after Fluent simulation was 8.1 卤1.52 m / s -6.7 卤0.45 m / s, respectively.The pressure drop in the vicinity of the spinous process was obvious, and the pressure in front of the spinous process increased during inspiratory period, and the area of decrease in pressure appeared behind the spinous process. On exhalation, the VAS score was opposite to the peak flow rate of inspiratory and expiratory phase and the velocity and pressure of airflow around the spinous process of nasal septum.The correlation analysis of Spearman grade and the distance between spinous process and anterior nasal spine was carried out. There was no significant correlation between Spearman and the above indexes.Conclusion the CFD model of nasal cavity of 36 patients with nasal septum deviation and 30 normal subjects was successfully established.The distribution of respiratory airflow in patients with spinous process of nasal septum is different from that in normal people. Spinous process obstructs the flow of normal airflow, changes the distribution of flow near spinous process and affects the distribution of internal pressure in nasal cavity, but the change of velocity and pressure has no significant correlation with nasal congestion symptoms.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R765

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