经甲状舌骨膜声带注射糖皮质激素治疗喉接触性肉芽肿

发布时间：2018-04-14 02:09

本文选题：声带注射术 + 甲状舌骨膜　；参考：《听力学及言语疾病杂志》2017年01期

【摘要】：目的初步探索经甲状舌骨膜(transthyrohyoid membrane approach,TH)声带注射术治疗喉接触性肉芽肿(又称声带突肉芽肿)的临床应用价值。方法回顾性分析2013年2月至2015年10月经TH径路声带病变内糖皮质激素注射术(醋酸曲安奈德注射液0.3~1mg,一次/月,至病变消失)配合抑酸疗法(口服埃索美拉唑片,20mg/次,早晚饭前半小时各一次)治疗的32例(34侧)喉接触性肉芽肿(laryngeal contact granuloma,LCG)患者的临床资料,随访14~44个月,中位时间26个月。应用Image J图像处理软件对患者病变组织范围进行测量,通过计算其与自身声带长度的比值来判断病变大小,分析其疗效。结果 32例34侧病变经TH法声带突肉芽肿注射曲安奈德,分别为1~6次,中位数3次,共113次,一次穿刺注射成功率100%,未出现并发症;治愈率64.71%(22/34),总有效率94.12%(32/34);疗程1~7月,平均3.32±1.34月。结论经TH法声带病变内糖皮质激素注射术配合抑酸疗法治疗喉接触性肉芽肿疗效确切,操作简便、准确,成功率高,疗程短,副作用少。
[Abstract]:Objective to explore the clinical value of transthyroid hyoid membrane acoustical injection in the treatment of laryngeal contact granuloma (also known as vocal cord granuloma).Methods from February 2013 to October 2015, glucocorticoid injection (triamcinolone acetonide acetate 0.31 mg, once a month, until the lesion disappeared) and acid-suppressive therapy (oral esomeprazole 20 mg / time) were retrospectively analyzed.The clinical data of 32 patients with laryngeal contact granulomatous LCGs treated once a half hour before early supper) were followed up for 14 ~ 44 months with a median time of 26 months.Image J image processing software was used to measure the range of lesion tissue in patients. The size of the lesion was judged by calculating the ratio of the lesion to the length of its own vocal cord and the curative effect was analyzed.Results Triamcinolone acetonide was injected into 34 sides of 32 cases with th method of vocal cord granuloma, with an average of 113 times (113 times). The success rate of single puncture injection was 100 times. The cure rate was 64.71% 22 / 34%, the total effective rate was 94.12% 32 / 34; the course of treatment ranged from 1 to 7 months, with an average of 3.32 卤1.34 months.Conclusion Intravocal glucocorticoid injection with th method in the treatment of laryngeal contact granuloma is effective, simple, accurate, high success rate, short course of treatment and less side effects.
【作者单位】：南方医科大学第三临床医学院;海军总医院全军耳鼻咽喉头颈外科中心;
【分类号】：R767.91

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