玻璃酸钠滴眼液治疗青少年近视患者配戴硬性透气性角膜接触镜相关性干眼

发布时间：2018-04-19 22:00

  本文选题：角膜塑形镜 + 玻璃酸钠滴眼液　； 参考：《国际眼科杂志》2016年03期

【摘要】：目的:观察1g/L玻璃酸钠滴眼液(不含防腐剂)对青少年近视患者配戴硬性透气性角膜接触镜(RGP)相关性干眼的疗效评价。方法:选择2015-01/05来我院门诊就诊的90例透气性角膜接触镜相关性干眼症近视患者,年龄12.75±4.15岁,屈光度-3.50±1.50D,患者均接受正规角膜塑形镜验配。将患者随机分为3组,每组30例60眼:A组使用RGP润滑液,4次/d,1滴/次;B组使用1g/L玻璃酸钠滴眼液(不含防腐剂),4次/d,1滴/次;C组在使用RGP润滑液(4次/d,1滴/次)后15min再用1g/L玻璃酸钠滴眼液(不含防腐剂)(4次/d,1滴/次)。观察各组患者用药前1d与用药后第1、2、4wk的眼部症状评分、Schirmer I试验(SⅠt)、泪膜破裂时间(BUT)、角膜荧光染色评分变化。结果:三组患者在用药1wk后的干眼症状、角膜荧光染色和BUT均较治疗前有明显的改善(PO.05),三组患者的SⅠt值治疗前后差异均无统计学意义(P0.05)。各组患者在治疗第2、4wk后和治疗1wk时测得的各项指标差异无统计学意义(P0.05)。B组与A组对干眼症状、SⅠt和BUT的改善作用差异无统计学意义(P0.05);B组较A组改善角膜荧光染色作用更明显,差异有统计学意义(P0.05)。C组对改善干眼症状和角膜荧光染色作用优于A组(PO.05)。C组对改善干眼症状上优于B组(P0.05)。结论:1g/L玻璃酸钠滴眼液(不含防腐剂)能够稳定泪膜,促进角膜上皮损伤愈合,改善青少年近视患者配戴硬性透气性角膜接触镜所致干眼症状,具有一定的临床应用价值。
[Abstract]:Objective: to evaluate the effect of 1g/L sodium hyaluronate eye drops (excluding preservatives) on dry eyes of juvenile myopia patients wearing rigid breathable contact lens. Methods: 90 patients with penetrating contact lens associated dry eye myopia, aged 12.75 卤4.15 years and diopter -3.50 卤1.50D, were selected from our outpatient clinic in 2015-01 / 05. The patients were randomly divided into three groups. Each group of 30 cases: 60 eyes: group A received RGP lubricant 4 times a drop per day, group B used 1g/L sodium hyaluronate eye drops (no preservatives 4 times per day per day), group C received 1g/L sodium hyaluronate after using RGP lubricating fluid for 4 times a drop per day. Eye fluid (not containing preservatives). The ocular symptom scores and the time of tear film rupture and corneal fluorescence staining were observed 1 day before and 2 weeks after treatment in each group. Schirmer I test was used to test S 鈪，

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