DWI在眼眶良恶性病变鉴别诊断中的应用

发布时间：2018-05-11 09:43

本文选题：眼眶病变 + 扩散加权成像　；参考：《临床放射学杂志》2017年05期

【摘要】：目的探讨扩散加权成像(DWI)和表观扩散系数(ADC)值在诊断及鉴别诊断眼眶良恶性病变中的价值。方法对78例眼眶病变患者于治疗前行常规MRI平扫和DWI检查,其中眼眶良性病变45例,恶性病变33例,测量病变的ADC均值,进行校正t检验统计处理和分析,运用受试者工作特征曲线(ROC)评价ADC值的诊断价值。结果良性病变ADC值为(1.42±0.36)×10~(-3)mm~2/s,恶性病变ADC值为(0.70±0.19)×10~(-3)mm~2/s,恶性病变ADC值明显低于良性病变(t值为-11.43,P=0.000)。ADC值诊断眼眶良恶性病变的ROC曲线下面积为0.978,ADC值以1.03×10~(-3)mm~2/s为阈值时,以病理结果为对照,判断眼眶病变良恶性的敏感度为93.3%,特异度为100%,准确率为96.2%,与病理结果行一致性检验,Kappa值为0.922。结论眼眶良恶性病变具有不同的扩散特征,ADC值对于两者之间的鉴别诊断具有重要参考价值,可提高诊断正确率。
[Abstract]:Objective to evaluate the value of diffusion weighted imaging (DWI) and apparent diffusion coefficient (ADCC) in the diagnosis and differential diagnosis of orbital benign and malignant lesions. Methods MRI plain scan and DWI examination were performed in 78 patients with orbital lesions before treatment. 45 cases of orbital benign lesions and 33 cases of malignant lesions were measured by ADC mean value and analyzed by corrected t test. The diagnostic value of ADC value was evaluated by using the operating characteristic curve of subjects. Results the ADC value of benign lesions was 1.42 卤0.36 脳 10 ~ (-3) mm ~ (-1) / s, the ADC value of malignant lesions was 0.70 卤0.19) 脳 10 ~ (-3) mm ~ (-1) / s. The ADC value of malignant lesions was significantly lower than that of benign lesions (t = -11.43 P ~ (0.000). The area under ROC curve was 0.978T when 1.03 脳 10~(-3)mm~2/s was used as a threshold value for diagnosis of benign and malignant orbital diseases. The sensitivity, specificity and accuracy of diagnosis of benign and malignant orbital lesions were 93. 3%, 100 and 96. 2% respectively. The Kappa value was 0. 922. Conclusion the ADC values of orbital benign and malignant lesions with different diffusive characteristics have important reference value for the differential diagnosis between the two and can improve the diagnostic accuracy.
【作者单位】：郑州大学第一附属医院磁共振科;
【分类号】：R445.2;R739.7

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