1型与2型糖尿病并发增生型糖尿病视网膜病变患者的眼生物学测量值比较

发布时间：2018-05-15 15:11

本文选题：增生型糖尿病视网膜病变 + 眼轴　；参考：《眼科新进展》2017年04期

【摘要】：目的评价1型与2型糖尿病并发增生型糖尿病视网膜病变(proliferative diabetic retinopathy,PDR)患者的眼生物学测量值的差异及其临床意义。方法回顾分析2014年9月至2016年7月我院收治的2型糖尿病并发PDR患者(年龄37~77岁)66例(67眼)、1型糖尿病并发PDR患者(年龄18~57岁)10例(19眼)及特发性黄斑裂孔患者(年龄21~74岁)35例(35眼)的眼轴长度、角膜内皮细胞数及年龄,比较三者之间生物学测量值差异性。结果1型糖尿病并发PDR患者眼轴长度为(21.74±0.68)mm,2型糖尿病并发PDR患者眼轴长度为(23.06±0.65)mm,特发性黄斑裂孔患者眼轴长度为(23.39±0.65)mm,三组数据差异具有统计学意义(P0.001)。三组患者角膜内皮细胞数比较差异无统计学意义(P=0.103)。三组患者年龄比较差异有统计学意义(P0.001)。结论1型与2型糖尿病并发PDR患者眼轴长度均小于正常眼轴长度,而1型糖尿病并发PDR患者眼轴较2型糖尿病并发PDR患者眼轴更短;且1型糖尿病并发PDR患者较2型糖尿病并发PDR患者发病时机早。
[Abstract]:Objective to evaluate the difference and clinical significance of ocular biological measurements in patients with proliferative diabetic retinopathy (PDR) between type 1 and type 2 diabetes mellitus complicated with proliferative diabetic retinopathy. Methods from September 2014 to July 2016, 66 patients with type 2 diabetes mellitus complicated with PDR (aged 3777 years) with type 1 diabetes mellitus complicated with PDR (10 eyes, 18 eyes, 57 years old) and idiopathic macular hole patients (19 eyes) were retrospectively analyzed. The axial length of 35 cases (35 eyes) aged 21 to 74 years. The number and age of corneal endothelial cells were compared. Results the length of eye axis in type 1 diabetes mellitus complicated with PDR was 21.74 卤0.68 mm and that in type 2 diabetes mellitus complicated with PDR was 23.06 卤0.65 mm and 23.39 卤0.65 mm in patients with idiopathic macular hole. The difference among the three groups was statistically significant (P 0.001). There was no significant difference in the number of corneal endothelial cells among the three groups. The age difference among the three groups was statistically significant (P 0.001). Conclusion the axial length of PDR in type 1 diabetes mellitus and type 2 diabetes mellitus complicated with PDR is shorter than that in type 1 diabetes mellitus complicated with PDR. The axial length of eye axis in type 1 diabetes mellitus complicated with PDR is shorter than that in type 2 diabetes mellitus complicated with PDR. The onset time of type 1 diabetes complicated with PDR was earlier than that of type 2 diabetes complicated with PDR.
【作者单位】：郑州大学第一附属医院眼科;
【分类号】：R587.2;R774.1

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