地塞米松不同时间间隔鼓室内灌注在治疗突发性聋中的临床研究

发布时间：2018-05-21 19:00

  本文选题：鼓室 + 地塞米松　； 参考：《临床耳鼻咽喉头颈外科杂志》2017年11期

【摘要】：目的:通过不同时间间隔鼓室内注射地塞米松治疗突发性聋的临床疗效对比,探讨鼓室内注射的适当时间间隔。方法:临床确诊160例突聋患者,除给予常规扩张血管、溶栓、高压氧治疗,同时给予鼓室腔内灌注地塞米松,按不同时间间隔分为3组。每日注射组:每日给予患耳鼓室腔内注射;隔日注射组:隔日注射;1周2次组:1周注射2次。另有全身使用激素组28例及未用激素组18例。共计206例患者。结果:每日注射组和隔日注射组疗效差异无统计学意义,与1周2次组、全身使用激素组及未用激素组比较,差异有统计学意义。结论:鼓室腔注射地塞米松临床应用广泛,操作简单,疗效明显,每日及隔日一次注射患者依从性好,疗效较1周2次明显,避免了全身使用糖皮质激素的不良反应,患者无明显痛苦,可推广应用。
[Abstract]:Objective: to study the appropriate time interval of intratympanic injection of dexamethasone in the treatment of sudden deafness. Methods: 160 patients with sudden deafness were treated with routine dilation, thrombolytic therapy, hyperbaric oxygen therapy and intracavitary infusion of dexamethasone. The injection group was treated with intracavitary injection of tympanum every day, and the injection group was injected twice a week with one week of injection every other day. There were 28 cases in the steroid group and 18 cases in the control group. A total of 206 patients were involved. Results: there was no significant difference in the curative effect between the daily injection group and the other day injection group. Conclusion: Dexamethasone injection into tympanic cavity is widely used in clinical application, simple operation and obvious curative effect. The compliance of daily and once injection is better than that of 2 times in 1 week, which avoids the adverse reaction of using glucocorticoid all over the body. The patient has no obvious pain and can be popularized and applied.
【作者单位】： 新疆石河子大学医学院第一附属医院耳鼻咽喉科;
【分类号】：R764.437
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本文编号：1920375