梅尼埃病不同听力分期中颈肌前庭诱发肌源性电位的差异

发布时间：2018-05-28 06:07

本文选题：梅尼埃病 + 听力　；参考：《临床耳鼻咽喉头颈外科杂志》2016年01期

【摘要】：目的:探讨不同听力分期梅尼埃病患者前庭肌源诱发电位的特征及临床意义。方法:纳入2015-01-2015-07期间就诊于第二军医大学眩晕诊治中心的79例单侧梅尼埃病患者,按听力分期分为轻度听力受损组41例(听力1期、2期)、中重度听力受损组38例(听力3期、4期),同时纳入正常对照组20例,在发作间期行颈肌前庭诱发肌源性电位(C-VEMP)检查。结果:C-VEMP引出率在轻度听力受损组与正常对照组间差异无统计学意义,在中重度听力受损组与轻度听力受损组及正常对照组间差异有统计学意义(P0.05)。P1、N1潜伏期在轻度听力受损组、中重度听力受损组和正常对照组间差异无统计学意义。P1-N1振幅以及振幅不对称比在轻度听力受损组与正常对照组间差异无统计学意义,中重度听力受损组与正常对照组及轻度听力受损组间差异有统计学意义(P0.05)。结论:随着梅尼埃病患者听力受损程度的加重,患者球囊功能损伤也随之加重。
[Abstract]:Objective: to investigate the characteristics and clinical significance of vestibular musculogenic evoked potential (VEP) in patients with Meniere's disease at different hearing stages. Methods: a total of 79 patients with unilateral Meniere's disease were enrolled in the diagnosis and treatment center of vertigo in the second military Medical University during the period 2015-01-2015-07. According to hearing stage, 41 cases were divided into mild hearing impairment group (hearing stage 1, stage 2), moderate and severe hearing impairment group (hearing stage 3, stage 4), and 20 cases were included in normal control group. C-VEMPs were performed during interictal period. Results there was no significant difference between mild hearing loss group and normal control group, but there was significant difference between moderate and severe hearing loss group and mild hearing loss group and normal control group. There was no significant difference between moderate and severe hearing loss group and normal control group. There was no significant difference in P1-N1 amplitude and amplitude asymmetry ratio between mild hearing loss group and normal control group. There was significant difference between moderate and severe hearing loss group, normal control group and mild hearing loss group (P 0.05). Conclusion: with the severity of hearing impairment in patients with Meniere's disease, the balloon dysfunction is aggravated.
【作者单位】：第二军医大学上海长征医院神经内科第二军医大学眩晕诊治中心;
【分类号】：R764.33

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