超高度近视眼视网膜神经纤维层厚度光学相干断层扫描的临床研究

发布时间：2018-05-29 21:26

本文选题：超高度近视 + 光学相干断层扫描　；参考：《中国斜视与小儿眼科杂志》2016年01期

【摘要】：目的探讨超高度近视眼视网膜神经纤维层厚度(RNFLT)光学相干断层成像(OCT)各个象限变化规律,为使用OCT检测超高度近视人群RNFLT诊断和鉴别诊断提供依据。方法选取正常对照组35例(55眼),超高度近视组57例(92眼),按等效球镜度分为三组:第I组:-10:00~-12.00D组,31例(57眼);第II组:-12.00~-15.00D组,15例(21眼);第III组:-15.00D组,11例(14眼)。采用OCT检测RNFLT,比较超高度近视患者RNFLT变化规律,并比较与正常对照组RNFLT的差别,研究超高度近视患者RNFLT与屈光度的相关性。结果超高度近视眼组与正常对照组相比除了颞侧RENFL平均厚度变薄。两组间对应的参数差异有统计学意义(P0.05)。超高度近视患者中在不同屈光度组RNFLT比较差异有统计学意义(P0.05),除了颞侧,屈光度的绝对值与RNFLT成负相关(r0,P0.05),鼻下相关性最高,颞上相关性较低。结论在超高度近视患者中,除了颞侧,OCT检测各个象限的RNFLT变薄。屈光度的绝对值与RNFLT成负相关。因此,在评价RNFLT改变时要重视超高度近视RNFLT的规律性特征。
[Abstract]:Objective to investigate the changes of retinal nerve fiber layer thickness (RNFT) optical coherence tomography (Oct) in ultra-high myopia and to provide evidence for the diagnosis and differential diagnosis of RNFLT by using OCT. Methods 35 cases of normal control group (55 eyes) and 57 cases of hypermyopia group (57 eyes) were divided into three groups according to the degree of equivalent spherical endoscopy: group I (31 cases, 57 eyes), group II (15 cases, 21 eyes), group 2: 12.00 (15 eyes), group 2 (11 cases, 15 eyes), III group (11 cases, 14 eyes). OCT was used to detect RNFLT in ultra-high myopia patients, and the difference between RNFLT and RNFLT was compared. The correlation between RNFLT and diopter was studied. Results the mean thickness of RENFL in the ultrahigh myopia group was thinner than that in the normal control group. The difference of corresponding parameters between the two groups was statistically significant (P 0.05). There was significant difference in RNFLT between the patients with ultra-high myopia and different diopter groups (P 0.05). Except for temporal side, the absolute value of diopter was negatively correlated with RNFLT (r 0 0 P 0 05), and the correlation was the highest in subnasal and lower in superior temporal. Conclusion in ultra-high myopia patients, RNFLT thinning is detected in all quadrants except temporal Oct. The absolute value of diopter was negatively correlated with RNFLT. Therefore, attention should be paid to the regular characteristics of ultra-high myopia RNFLT when evaluating the changes of RNFLT.
【作者单位】：哈尔滨医科大学附属第一医院眼科视光学中心;
【分类号】：R778.11

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