体位性与非体位性OSAHS患者接受低温等离子辅助UPPP疗效观察

发布时间：2018-06-04 07:49

本文选题：睡眠呼吸暂停低通气综合征 + 阻塞性　；参考：《重庆医学》2017年07期

【摘要】：目的探讨低温等离子辅助悬雍垂腭咽成形术(UPPP)对体位性和非体位性阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者的治疗效果。方法选择该院2014年1月至2015年12月经多导睡眠呼吸监测(PSG)确诊为OSAHS并接受低温等离子辅助UPPP的患者26例,根据不同睡眠体位状态下呼吸暂停低通气指数(AHI)将OSAHS患者分为体位性睡眠呼吸暂停(PPs)组、非体位性睡眠呼吸暂停(NPPs)组,比较两组患者手术前、后AHI变化及手术有效率。结果 PPs组总AHI、仰卧位AHI(S-AHI)、侧卧位AHI(L-AHI)均低于NPPs组(P0.05),且血氧相关指标高于NPPs组(P0.05);OSAHS患者手术总有效率为73.08%(19/26),其中PPs组手术有效率为100%(7/7),NPPs组手术有效率为63.16%(12/19),但两组患者手术有效率比较差异无统计学意义(P=0.13)。与手术前比较,两组患者手术后总AHI、S-AHI、L-AHI均下降(P0.05);NPPs组L-AHI下降幅度明显高于S-AHI[0.96(0.86,1.00)vs.0.53(0.34,0.77),P0.01]。NPPs组中术后有78.95%(15/19)转变为PPs。结论低温等离子辅助UPPP治疗对OSAHS患者有一定治疗效果,其中NPPs患者受益更明显。
[Abstract]:Objective to investigate the therapeutic effect of hypothermic plasma assisted uvulopalatopharyngoplasty (UPPP) on patients with postural and non-postural obstructive sleep apnea hypopnea syndrome (OSAHS). Methods from January 2014 to December 2015, 26 patients with OSAHS and received hypothermic plasma assisted UPPP were selected. According to apnea hypopnea index (AHII) in different sleep posture, OSAHS patients were divided into two groups: postpositional sleep apnea group and non-postpositional sleep apnea group. The changes of AHI before and after operation and the effective rate were compared between the two groups. Results in the PPs group, the total AHI, the supine AHIS AHIN and the lateral lying AHIG L-AHI) were lower than those in the NPPs group (P 0.05), and the blood oxygen related indexes were higher than that in the NPPs group. The total effective rate was 73.08 卤19 / 26 in the PPs group, and the effective rate in the PPs group was 63.16% 12 / 19%, but the operative response rate was 63.16% in the PPs group, but the total effective rate was 73.08% / 26% in the NPPs group. There was no significant difference in efficiency. Compared with those before operation, the decrease of L-AHI in the total AHI S-AHIN L-AHI group after operation was significantly higher than that in the S-AHI group [0.96 卤0.86 卤1.00 vs.0.530.34 卤0.77 P0.01]. In the NPPs group, 78.9515% of the patients changed to PPs after operation. Conclusion the hypothermic plasma-assisted UPPP therapy has some therapeutic effect on OSAHS patients, and the benefit of NPPs patients is more obvious.
【作者单位】：广州医科大学附属第一医院广州呼吸疾病研究所;广州医科大学附属第一医院耳鼻咽喉头颈外科;
【分类号】：R766.9

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