康柏西普对增殖型糖尿病视网膜病玻璃体切割术的影响

发布时间：2018-06-12 09:01

本文选题：糖尿病视网膜病变 + 璃体切除术　；参考：《福建医科大学学报》2017年03期

【摘要】：目的观察康柏西普眼内注射对增殖型糖尿病视网膜病(PDR)玻璃体切割手术(PPV)的影响。方法 2014年5月-2016年5月,因PDR行PPV联合硅油注入手术的患者共53例(53眼),按是否进行术前玻璃体腔康柏西普注射,分为单纯PPV组(A组)28例(28眼)及康柏西普玻璃体腔注射联合PPV组(B组)25例(25眼),回顾性分析2组患者的临床资料,并比较2组患者在术中累计出血量、手术时间及术后1周、1月及3月时视网膜出血、视网膜增殖及视力预后的情况。结果 B组的手术时间、术中累计出血量均少于A组(P0.05);术后1周时,B组视网膜出血例数少于A组,平均视力高于A组(P0.05),而视网膜增殖方面2组差别无统计学意义;术后1及3月时,B组较A组视网膜增殖少,视力预后更好(P0.05),而视网膜出血情况2组差别无统计学意义。结论在PDR患者行PPV手术中,术前眼内注射康柏西普可减少术中出血、缩短手术时间、减少术后再出血、减轻视网膜增殖,并能获得更佳的术后视力,为PDR患者保留相对较佳的视功能。
[Abstract]:Objective To observe the effect of compaitcept intraocular injection on vitrectomy (PPV) for proliferative diabetic retinopathy (PDR). Methods in May -2016 May 2014, 53 patients (53 eyes) with PDR PPV combined with silicone oil injection were divided into 28 cases (28 eyes) and Compaq in group PPV (group A) according to whether the anterior vitreous coelous cicopcept was injected before operation. Cept combined with PPV group (group B) (group B) 25 cases (25 eyes), retrospective analysis of the clinical data of 2 groups of patients, and compared the total amount of bleeding in the 2 groups, operation time and 1 weeks after operation, retinal hemorrhage, retinal proliferation and visual prognosis in January and March. Results the operation time of group B, the total amount of bleeding in the operation was less than group A (P 0.05): at 1 weeks after operation, the number of retinal hemorrhage in group B was less than that in group A, the average visual acuity was higher than that of group A (P0.05), but there was no significant difference between the 2 groups of retina proliferation. At 1 and March after the operation, the retina proliferated less and the prognosis of the retina was better than the A group (P0.05), but there was no statistical difference between the 2 groups of the retinal blood condition. Conclusion in the PPV operation of PDR patients, there was no statistical significance. Intraocular injection of compaitcept before operation can reduce intraoperative bleeding, shorten operation time, reduce postoperative rebleeding, reduce retinal proliferation, and obtain better postoperative visual acuity, so as to retain a relatively good visual function for PDR patients.
【作者单位】：恩施土家族苗族自治州中心医院眼科;
【基金】：湖北省卫生和计划生育委员会立项项目(WJ2015MB194)
【分类号】：R587.2;R779.6

【相似文献】