良性阵发性位置性眩晕的前庭诱发肌源电位和前庭双温交替试验特性研究

发布时间：2018-06-20 08:15

本文选题：良性阵发性位置性眩晕 + 前庭功能　；参考：《福建医科大学》2012年硕士论文

【摘要】：目的： 1.研究cVEMP oVEMP和BT的检测方法和反应特性，探讨正常人群的cVEMP、oVEMP和BT是否受性别、年龄和耳间差异的影响； 2．研究BPPV患者的cVEMP、oVEMP和BT的反应特性，，并通过与正常人群的各项检测数据的对比，探讨cVEMP、oVEMP和BT变化对眩晕定位诊断和预后评估的意义。方法：对64例正常人按不同性别、不同年龄和不同耳别分别进行cVEMP、oVEMP和BT检测。对33例BPPV患者患耳的cVEMP oVEMP和BT检测数据分别与健耳和正常人群耳的检测数据进行对比，分析比较不同组别之间各项检测数据的差异。结果： 1．正常人群组不同性别、左右耳间cVEMP、oVEMP和BT试验的各项检测数据无显著性差异，不同年龄段cVEMP、oVEMP的潜伏期和BT的SPV无显著性差异，但不同年龄段cVEMP、oVEMP的峰－峰振幅差异有显著性意义。 2．病例组患耳的cVEMP、oVEMP各项检测数据与正常人群耳对比，差别有显著性意义。但两组间BT的SPV无显著性差异。 3．病例组患耳和健耳的cVEMP、oVEMP各项检测数据对比差异有显著性意义，但两组间BT的SPV无显著性差异。 4．病例组患耳的cVEMP、oVEMP异常率分别达到33%和36%，CP阳性率达到48%。结论： 1．正常人群不同年龄段峰－峰振幅差异有显著性意义，年龄与振幅呈负相关，说明振幅随年龄的增长而降低。 2．病例组患耳的cVEMP、oVEMP各项检测数据与健耳和正常人群耳的检测数据对比差异有显著性意义，但不同组间BT的SPV无显著性差异。病例组患耳的cVEMP、oVEMP异常率分别达到33%和36%，CP阳性率达到48%。说明cVEMP、oVEMP和BT可以作为BPPV前庭功能状态的客观量化评估指标。 3.对BPPV患者进行cVEMP、oVEMP和BT检测的结果表明对前庭球囊、椭圆囊和半规管的病理状态和功能变化可以获得客观评价数据，提示上述三项检查方法对眩晕患者的定位诊断有一定的临床价值，进而可为眩晕治疗的疗效和预后判断提供客观依据。
[Abstract]:Objective: 1. To study the detection methods and response characteristics of cVEMP oVEMP and BT, and to investigate whether cVEMPOVEMP and BT are affected by sex, age and ear difference in normal population. 2. To study the response characteristics of cVEMPoVEMP and BT in patients with BPPV. The significance of the changes of cVEMPO VEMP and BT in the diagnosis and prognosis of vertigo was discussed. Methods: 64 normal subjects were tested for cVEMPoVEMP and BT according to sex, age and ear type. The data of camp oVEMP and BT in 33 patients with BPPV were compared with those of healthy ears and normal ears, and the differences among different groups were analyzed. Results: 1. There was no significant difference in the detection data between right and left ears of cVEMPOVEMP and BT test, but there was no significant difference in latency of camp and SPV between different age groups. 2. However, there were significant differences in peak to peak amplitudes of cVEMPG oVEMP in different age groups. 2. There was significant difference between the data of cVEMP and oVEMP in patients with different age groups compared with that of normal subjects. However, there was no significant difference in SPV between the two groups. 3. There was significant difference in the detection data of cVEMPOVEMP between the affected ears and healthy ears. However, there was no significant difference in SPV between the two groups. 4. The abnormal rate of cVEMPOVEMP in the affected ears reached 33% and 36% respectively. Conclusion: 1. There was significant difference between peak amplitude and peak amplitude in different age groups in normal population, and age was negatively correlated with amplitude. 2. The amplitude decreased with the increase of age. 2. There was a significant difference between the measured data of cVEMPOVEMP and that of healthy and normal ears, but there was no significant difference in SPV of BT between different groups. The abnormal rates of cVEMPOVEMP in the affected ears were 33% and 36%, respectively. It shows that cVEMPOVEMP and BT can be used as objective quantitative evaluation indexes of vestibular function status of BPPV. The results of cVEMPOVEMP and BT in BPPV patients showed that the pathological state and function of vestibular balloon, elliptical sac and semicircular canal could be evaluated objectively. The results suggest that the above three methods have certain clinical value in the localization diagnosis of vertigo patients, and can provide objective basis for the treatment of vertigo and the judgment of prognosis.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R764.3

【参考文献】

中国期刊全文数据库前10条

1 林韵琪;叶青;李瑞玉;曾国胜;;110例良性阵发性位置性眩晕患者双温试验分析[J];福建医药杂志;2010年06期

2 吴子明;耳石器功能的临床检查[J];国外医学(耳鼻咽喉科学分册);2003年04期

3 蒋月星,董雪蕾,李和安;50岁以上健康人温度试验的眼震电图诸参数变化[J];临床耳鼻咽喉科杂志;1998年01期

4 庄建华;黄坚;赵忠新;赵瑛;周辉;王文昭;田国红;;水平半规管良性发作性位置性眩晕的临床研究[J];临床神经病学杂志;2005年06期

5 吴子明,张素珍,杨伟炎,韩东一;耳石器相关的疾病[J];听力学及言语疾病杂志;2003年02期

6 马鑫;郑宏伟;余力生;;正常人双温试验反应强度和年龄的相关性分析[J];听力学及言语疾病杂志;2008年04期

7 粟秀初;眩晕的临床诊断[J];中国现代神经疾病杂志;2005年05期

8 谢溯江;郑颖鹃;贾宏博;;前庭诱发的肌源性电位新进展[J];中国眼耳鼻喉科杂志;2009年04期

9 贾宏博,郭世俊,谢溯江,毕红哲,刘广莉,王锦铃,于立身,吴子明;主观重力垂直线知觉检查及其常值标准[J];中华航空航天医学杂志;2005年01期

10 朱素琴,常伟,李骏,黄治物;眼震电图600例分析[J];中国民政医学杂志;2001年06期