良性阵发性位置性眩晕的前庭诱发肌源电位和前庭双温交替试验特性研究

发布时间：2018-06-20 08:15

本文选题：良性阵发性位置性眩晕 + 前庭功能　；参考：《福建医科大学》2012年硕士论文

【摘要】：目的： 1.研究cVEMP oVEMP和BT的检测方法和反应特性，探讨正常人群的cVEMP、oVEMP和BT是否受性别、年龄和耳间差异的影响； 2．研究BPPV患者的cVEMP、oVEMP和BT的反应特性，并通过与正常人群的各项检测数据的对比，探讨cVEMP、oVEMP和BT变化对眩晕定位诊断和预后评估的意义。方法：对64例正常人按不同性别、不同年龄和不同耳别分别进行cVEMP、oVEMP和BT检测。对33例BPPV患者患耳的cVEMP oVEMP和BT检测数据分别与健耳和正常人群耳的检测数据进行对比，分析比较不同组别之间各项检测数据的差异。结果： 1．正常人群组不同性别、左右耳间cVEMP、oVEMP和BT试验的各项检测数据无显著性差异，不同年龄段cVEMP、oVEMP的潜伏期和BT的SPV无显著性差异，但不同年龄段cVEMP、oVEMP的峰－峰振幅差异有显著性意义。 2．病例组患耳的cVEMP、oVEMP各项检测数据与正常人群耳对比，差别有显著性意义。但两组间BT的SPV无显著性差异。 3．病例组患耳和健耳的cVEMP、oVEMP各项检测数据对比差异有显著性意义，，但两组间BT的SPV无显著性差异。 4．病例组患耳的cVEMP、oVEMP异常率分别达到33%和36%，CP阳性率达到48%。结论： 1．正常人群不同年龄段峰－峰振幅差异有显著性意义，年龄与振幅呈负相关，说明振幅随年龄的增长而降低。 2．病例组患耳的cVEMP、oVEMP各项检测数据与健耳和正常人群耳的检测数据对比差异有显著性意义，但不同组间BT的SPV无显著性差异。病例组患耳的cVEMP、oVEMP异常率分别达到33%和36%，CP阳性率达到48%。说明cVEMP、oVEMP和BT可以作为BPPV前庭功能状态的客观量化评估指标。 3.对BPPV患者进行cVEMP、oVEMP和BT检测的结果表明对前庭球囊、椭圆囊和半规管的病理状态和功能变化可以获得客观评价数据，提示上述三项检查方法对眩晕患者的定位诊断有一定的临床价值，进而可为眩晕治疗的疗效和预后判断提供客观依据。
[Abstract]:Purpose :

1 . To study the detection methods and reaction characteristics of cVEMP oVEMP and BT , and explore whether the cVEMP , oVEMP and BT of normal population are affected by sex , age and ear difference ;

2 . To study the reaction characteristics of cVEMP , oVEMP and BT in patients with BPPV , and to explore the significance of cVEMP , oVEMP and BT changes in diagnosis and prognosis of vertigo by comparing with the detection data of normal population .

Method :

The cVEMP , oVEMP and BT test were performed on 64 healthy subjects with different sex , age and ear respectively . The cVEMP oVEMP and BT test data of 33 patients with BPPV were compared with the detection data of healthy ear and normal ear respectively .

Results :

1 . There was no significant difference in the test data of cVEMP , oVEMP and BT in normal population group . There was no significant difference in the latency of cVEMP and oVEMP in different age groups , but the peak - to - peak amplitude of oVEMP in different age groups was significant .

2 . The cVEMP and oVEMP were significantly different between the two groups , but there was no significant difference between the two groups .

3 . There was a significant difference in cVEMP and oVEMP in the case group and the healthy ear , but there was no significant difference between the two groups .

4 . The abnormal rates of cVEMP and oVEMP were 33 % and 36 % , and the positive rate of CP was 48 % .

Conclusion :

1 . The difference of the peak - to - peak amplitude of the normal population was significant , and the age was negatively correlated with the amplitude , indicating that the amplitude decreased with age .

2 . The cVEMP and oVEMP in the case group were significantly different from those of healthy ear and normal ear , but there was no significant difference between different groups . The abnormal rates of cVEMP and oVEMP in the case group were 33 % and 36 % , and the positive rate of CP reached 48 % . The cVEMP , oVEMP and BT could be used as objective quantitative assessment indexes of the functional status of BPPV vestibular function .

3 . The results of cVEMP , oVEMP and BT test in BPPV patients show that the objective evaluation data can be obtained for the pathological states and function changes of vestibular balloon , oval capsule and semicircular canal . It is suggested that the above three methods can provide an objective basis for the diagnosis of vertigo .
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R764.3

【参考文献】