血液标志物对鼻咽癌预后的研究进展

发布时间：2018-06-25 09:33

  本文选题：鼻咽癌 + nasopharyngeal　； 参考：《广东医学》2017年19期

【摘要】：正鼻咽癌(nasopharyngeal carcinoma,NPC)的临床症状、体征复杂多变,具有恶性程度高、颈部淋巴结转移早、远处转移发生率高等临床特点。随着影像学、放疗技术的进步以及化疗在局部晚期NPC患者中的应用,其生存率得到了明显的提高,但治疗后局部复发和远处转移仍然是NPC治疗失败的主要原因。目前NPC的预后预测主要是依据美国癌症联合委员会(American Joint Cancer Committee,AJCC)制定的TNM(tumor-node metastasis)分期系统。然而有研究报道即使是同一分期的患者,其预后也可能会有显著差异。因此,筛选出有效并能准确地预测NPC预后的因素,对制定个体化
[Abstract]:The clinical symptoms and signs of nasopharyngeal carcinoma (NPC) are complex and changeable, with high degree of malignancy, early cervical lymph node metastasis and high incidence of distant metastasis. With the development of imaging, radiotherapy and the application of chemotherapy in local advanced NPC patients, the survival rate has been significantly improved, but local recurrence and distant metastasis are still the main reasons for the failure of NPC treatment. At present, the prognosis of NPC is mainly based on the TNM (tumor-node metastasis) staging system developed by the American Joint Cancer Committee (AJCC). However, studies have reported significant differences in prognosis even in patients with the same staging. Therefore, the factors that can predict the prognosis of NPC effectively and accurately are screened out.
【作者单位】： 赣州市人民医院肿瘤科;
【分类号】：R739.63

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