养阴活血通络明目合剂治疗2型糖尿病并视网膜病变的临床研究

发布时间：2018-06-27 22:30

  本文选题：2型糖尿病并视网膜病变 + 养阴活血通络明目合剂　； 参考：《山东中医药大学》2012年硕士论文

【摘要】：目的：观察养阴活血通络明目合剂对2型糖尿病并视网膜病变的影响。 方法：本研究纳入的60例2型糖尿病并视网膜病变的患者均来自山东中医药大学附属医院内分泌科门诊及病房。随机将其分为两个组：对照组30例给予基础治疗，即在标准的饮食和运动计划基础上，给予芪明颗粒治疗；治疗组30例在上述基础治疗基础上，给予养阴活血通络明目合剂，4个周为一个疗程，连续服用二个疗程。 结果：经过临床研究，治疗组与对照组在降低血糖水平以及改善糖化血红蛋白上均有疗效，，但治疗组的疗效明显优于对照组（P0.01）；在改善视网膜病变疗效以及血流变指标方面优于对照组（P0.05），并且在治疗过程中未发生不良反应。 结论：临床观察表明，养阴活血通络明目合剂治疗2型糖尿病并视网膜病变有明显的临床疗效，在改善患者的血糖、血脂、血液流变学指标方面也起到了积极的作用，且在治疗过程中未发生明显的不良反应，值得进一步研究。
[Abstract]:Objective: to observe the effect of Yangyin Huoxue Tongluo Mingmu mixture on type 2 diabetes mellitus complicated with retinopathy. Methods: 60 patients with type 2 diabetes complicated with retinopathy were collected from the Department of Endocrinology, Shandong University of traditional Chinese Medicine. They were randomly divided into two groups: the control group (30 cases) was treated with basic treatment, that is, Qiming granule was given on the basis of standard diet and exercise plan, and the treatment group (30 cases) was treated with Qiming granule on the basis of the above basic treatment. Nourishing Yin, activating blood circulation, clearing the collaterals and eyes mixture, 4 weeks as a course of treatment, two consecutive courses of treatment. Results: after clinical study, both the treatment group and the control group were effective in reducing blood sugar level and improving glycosylated hemoglobin, but the curative effect of the treatment group was obviously better than that of the control group (P0.01). It was superior to the control group in improving the curative effect and hemorheological index of retinopathy (P0.05), and there was no adverse reaction in the course of treatment. Conclusion: the clinical observation shows that Yangyin Huoxue Tongluo Mingmu mixture has obvious clinical effect in the treatment of type 2 diabetes mellitus with retinopathy, and it also plays an active role in improving the blood sugar, blood lipid and hemorheology of the patients. There was no obvious adverse reaction in the course of treatment, which is worthy of further study.
【学位授予单位】：山东中医药大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R774.1

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