二氧化碳激光辅助下外层Schlemm管消融术短期安全性及有效性评价

发布时间：2018-06-28 17:20

本文选题：青光眼 + 二氧化碳激光辅助下外层Schlemm管消融术　；参考：《眼科学报(英文版)》2016年04期

【摘要】：目的:评价药物治疗无效的开角型青光眼及部分复杂性青光眼行二氧化碳激光辅助下外层Schlemm管消融术(CO_2 laser-assisted sclerectomy surgery,CLASS)的短期临床安全性及有效性。方法:收集2015年5月至2016年1月解放军总医院眼科行CLASS手术和小梁切除手术的青光眼患者各23例,共46例46只眼。观察术后1周、1个月和3个月眼压及并发症发生情况。结果:两组术后1周、1个月及3个月眼压较术前均明显下降(P=0.000)。术后1周、1个月及3个月时CLASS手术组眼压平均值均低于小梁切除术组,但无统计学差异(P0.05)。CLASS手术组23例均无浅前房、脉络膜脱离等并发症出现。小梁切除手术组有4例在术后早期出现浅前房,其中1例出现脉络膜脱离,经治疗后均治愈。结论:CLASS手术在有效降低眼压的同时,能大幅降低患者术后出现浅前房等并发症的概率,但其远期降眼压效果及并发症发生情况有待进一步深入研究。
[Abstract]:Objective: to evaluate the short-term clinical safety and efficacy of CO _ 2 laser-assisted sclerectomy surgeryCLASS in patients with open angle glaucoma and partially complicated glaucoma treated with CO _ 2 laser-assisted sclerectomy laser assisted with CO _ 2 laser. Methods: from May 2015 to January 2016, 23 glaucoma patients (46 eyes of 46 cases) received class operation and trabeculectomy in PLA General Hospital. Intraocular pressure and complications were observed 1 week, 1 month and 3 months after operation. Results: IOP in both groups was significantly decreased at 1 week, 1 month and 3 months after operation (P0. 000). At 1 week, 1 month and 3 months after operation, IOP in CLASS group was lower than that in trabeculectomy group, but there was no statistical difference (P0.05). There were no superficial anterior chamber, choroidal detachment and other complications in CLASS group. In trabeculectomy group, 4 cases had shallow anterior chamber early after operation, and 1 case had choroidal detachment. All cases were cured after treatment. Conclusion while reducing intraocular pressure effectively, the probability of complications such as shallow anterior chamber after operation can be significantly reduced by the operation of W1 class. However, the long-term effect of reducing IOP and the occurrence of complications need to be further studied. [WT5HZ] [WT5 "BZ] [WT5" HZ]
【作者单位】：解放军总医院眼科;

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