慢性鼻-鼻窦炎上颌窦口黏膜固有层病理学改变与预后之间的关系

发布时间：2018-07-03 04:39

  本文选题：慢性鼻-鼻窦炎 + 黏膜　； 参考：《中国耳鼻咽喉颅底外科杂志》2016年01期

【摘要】：目的探讨慢性鼻-鼻窦炎上颌窦口黏膜固有层病理学改变与鼻内镜手术预后之间的关系,通过有意义的病理学指标以指导对该病的临床诊治。方法选取接受鼻内镜鼻窦手术的慢性鼻-鼻窦炎患者50例,术中取所选上颌窦口黏膜,进行HE染色,观察其固有层腺体面积与炎细胞数量2个病理学指标,术后6个月利用SNOT-20量表和Lund-Kennedy评分对所选患者进行疗效评估。结果慢性鼻-鼻窦炎患者的术后症状改善的好坏与黏膜固有层腺体面积直接相关(P0.05),而与固有层炎细胞数量无直接关联(P0.05)。结论黏膜固有层腺体面积是反映鼻窦疾病严重程度的重要指标,能够反映患者预后情况,对鼻内镜手术疗效的预测具有重要意义。
[Abstract]:Objective to investigate the relationship between the pathological changes of the mucosal lamina propria of maxillary sinusitis and the prognosis of endoscopic sinus surgery in patients with chronic rhinosinusitis. Methods 50 patients with chronic rhinosinusitis underwent endoscopic sinus surgery were selected. The maxillary sinus mucosa was selected for HE staining. The area of the lamina propria and the number of inflammatory cells were observed. SNOT-20 scale and Lund Kennedy score were used to evaluate the curative effect of the selected patients 6 months after operation. Results the improvement of postoperative symptoms in patients with chronic rhinosinusitis was directly related to the area of glands in the lamina propria (P0.05), but not to the number of cells in laminitis propria (P0.05). Conclusion the area of the mucosal lamina propria is an important index to reflect the severity of sinus disease and can reflect the prognosis of the patients. It is of great significance to predict the outcome of endoscopic sinus surgery.
【作者单位】： 河北北方学院附属第一医院耳鼻咽喉头颈外科;
【分类号】：R765.9
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本文编号：2092429