自动调压模式及固定压力模式CPAP对OSAHS患者治疗效果的meta分析

发布时间：2018-07-08 15:56

  本文选题：阻塞性睡眠呼吸暂停 + Auto-CPAP　； 参考：《昆明医科大学》2017年硕士论文

【摘要】：=6.71;P0.00001]及[MD=0.25;95%CI(0.00,0.50);Z=1.95;P=0.05]),其余亚组结果均显示两种模式对OSAHS治疗无明显差异。1.2 Epworth 嗜睡量表(Epworth Sleepiness Scale,ESS)总体结果显示Auto-CPAP较Fixed-CPAP改善了治疗ESS,两者间有显著差异[MD=-0.38;95%CI(-0.46,-0.29);Z=8.59;P0.00001],其中在治疗前 AHI 处于20～30亚组中,Fixed CPAP较Auto-CPAP更能改善治疗后ESS值[MD=0.76;95%CI(0.33,1.20);Z=3.42;P=0.0006],在治疗前 AHI 处于 30～40 亚组及40～50亚组中 Auto-CPAP较Fixed CPAP改善了患者治疗后ESS([MD =-0.50;95%CI(-0.61,-0.40);Z=9.60;P0.00001]及[MD=-0.30;95°%%CI(-0.50,-0.11);Z=3.10;P=0.002])。2.依从性对比总体结果显示Auto-CPAP较Fixed CPAP治疗后依从性较好,两者间有显著差异[MD=0.23h/夜;95%CI(0.10,0.35);Z=3.42;P=0.0006],其中20AHI≤30亚组及30AHI≤40亚组中提示Auto-CPAP较Fixed CPAP患者提高患者治疗依从性([MD=0.52;95%CI(0.38,0.66);Z=7.24;P0.00001]及[MD=0.20;95%CI(0.14,0.26);Z=6.70;P0.0001]),其余亚组两者对患者治疗依从性无明显差异影响。3.生活质量对比结果显示Auto-CPAP与Fixed CPAP对OSAHS患者治疗后睡眠呼吸暂停生活质量指数(Sleep Apnea Quality of Life Index,SAQLI)、功能评估性睡眠问卷(Functional Outcomes of Sleep Questionnaire, FOSQ)、美国医学结局研究组的36 项问卷简表精力方面(Mos 36-item short-form health survey Vitality,SF-36 Vitality )差异均无统计学意义([MD=0.01 ;95%CI(-0.08,0.09);Z=0.14;P=0.89]、[MD=-0.13;95%CI(-0.66,0.41);Z=0.46;P=0.65]及[MD=-0.39;95%CI(-1.52,0.75);Z=0.67;P=0.50])。[结论]Auto-CPAP与Fixed CPAP相比较,Auto-CPAP提高了患者的治疗后ESS,提高了患者治疗的依从性,对患者治疗后AHI无明显差异;生活质量方面,两种模式对OSAHS患者治疗后SAQLI.FOSQ.SF-36 Vitality均无明显差异。
[Abstract]:The results of other subgroups showed that there was no significant difference between the two models in the treatment of OSAHS. The overall results of Epworth Sleepiness ScaleESS showed that Auto-CPAP improved the treatment of ESSs compared with Fixed-CPAP, and there was a significant difference between the two subgroups [MD-0.3895CI (-0.46- 0.29) Z8.59P0.00001]. 30浜氱粍涓，

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