不同程度阻塞性睡眠呼吸暂停低通气综合征的心率变异性分析

发布时间：2018-07-22 10:18

【摘要】：目的探讨心率变异性对不同程度阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea-hypopnea syndrome,OSAHS)患者心功能诊断与评估的临床价值。方法 119例OSAHS患者根据睡眠呼吸暂停低通气指数(apnea-hypopnea index,AHI)分为对照组、轻度组、中度组、重度组,完善所有患者颈围、体重指数信息,并进行多导睡眠图检查和心率变异性分析。结果OSAHS疾病程度与颈围、体重指数及AHI均呈正相关(r=0.763,0.615,0.825,P0.05);与昼、夜24小时内每5分钟节段平均常RR间期标准差(standard deviation of all the 5-minaverage ofN-N interval,SDANN_昼、SDANN_夜)呈正相关(r=0.821,0.793,P0.05);与昼、夜低频能(low frequency energy,LF_昼、LF_夜)以及昼高频能(high frequency energy,HF_昼)呈正相关(r=0.534,0.829,0.645,P0.05);但与昼、夜全程RR间期差值的均方根(root mean square of successive N-N interval difference,rMSSD_昼、rMSSD_夜)、HF夜呈负相关(r=-0.652,-0.871,-0.738,P0.05)。结论心率变异性分析能有效反映心脏自主神经张力的变化,结合颈围、AHI、体重指数,对OSAHS患者疾病程度分级与治疗具有指导意义。
[Abstract]:Objective to investigate the clinical value of heart rate variability (HRV) in the diagnosis and evaluation of cardiac function in patients with obstructive sleep apnea hypopnea syndrome (obstructive sleep apnea-hypopnea syndromes). Methods according to apnea-hypopnea apnea hypopnea index (apnea-hypopnea), 119 patients were divided into control group, mild group, moderate group and severe group. Results the degree of OSAHS disease was positively correlated with neck circumference, BMI and AHI (r = 0.763n 0.615 卤0.825), and with the average mean RR interval (standard deviation of all the 5-minaverage of N-N intervaln SDANN _ day SDANN _ night) in 24 hours of day and night (r 0.821 ~ 0.793g). There was a positive correlation between low-frequency (low frequency energy and high-frequency daytime energy (high frequency energy HFL _ night (r = 0.534) (r = 0.534), but a negative correlation between RMS N-N interval difference (root mean square of successive N-N interval difference interval) and daytime (r = 0.652U -0.871U -0.738m). Conclusion Heart rate variability analysis can effectively reflect the changes of cardiac autonomic nervous tension. Combined with AHI and body mass index, it has guiding significance for the classification and treatment of OSAHS patients.
【作者单位】：湖北省襄阳市中心医院耳鼻喉科;
【分类号】：R766

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