变应性鼻炎患病率及危险因素Meta分析

发布时间：2018-07-28 18:14

【摘要】：目的:通过Meta分析,了解中国变应性鼻炎(AR)的患病率及探讨国内人群AR的主要危险因素,为AR的防治提供科学依据。方法:系统检索Pubmed、Embase、Web of science、Cochrane图书馆、相关期刊论文、中文科技期刊全文数据库、万方数字化期刊全文数据库、中国生物医学文献数据库等数据库查找关于中国AR患病率及危险因素相关文献,同时追索纳入文献的参考文献。采用R3.2.3软件对各研究结果进行Meta分析。结果:共纳入31篇文献,国内儿童AR患病率为15.79%(95%CI 15.13~16.45),华中地区患病率最高(17.20%),华东最低(13.94%)。成人AR患病率为13.26%(95%CI 12.05~14.47),华南地区患病率最高(15.45%),西南最低(10.93%)。各危险因素合并比值比(OR)分别为家族史(5.40)、粉尘接触史(2.04)、药物过敏史(2.83)、哮喘病史(4.45)、环境烟草烟雾(2.00)、水泛滥(1.50)、装修(1.41)、花粉过敏(17.18)、真菌(1.31)、饲养宠物(1.29)、蟑螂(1.69)。结论:中国AR的流行趋势研究发现,国内儿童AR患病率高于成人,不同地区患病率有差异,上述11种危险因素在AR的发病中起重要作用,在AR的防治过程中应针对这些危险因素进行早期干预。
[Abstract]:Objective: to investigate the prevalence of allergic rhinitis (AR) and the main risk factors of AR in Chinese population by Meta analysis, and to provide scientific basis for the prevention and treatment of AR. Methods: Pubmedmedus Embase Web of Science Cochrane Library, full text Database of Chinese Journals, full text Database of Chinese Sci-tech Journals, full text Database of Wanfang Digital Journals were searched systematically. The Chinese Biomedical Literature Database and other databases were used to search the literature about the prevalence and risk factors of AR in China. The results were analyzed by Meta with software R3.2.3. Results: the prevalence rate of AR in Chinese children was 15.79% (95%CI 15.1316.45), the highest in central China (17.20%), and the lowest in East China (13.94%). The prevalence of AR in adults was 13.26% (95%CI 12.05 ~ 14.47), the highest in South China (15.45%), and the lowest in Southwest (10.93%). The relative ratios of (OR) to (OR) were family history (5.40), dust exposure history (2.04), drug allergy history (2.83), asthma history (4.45), environmental tobacco smoke (2.00), flooding (1.50), decoration (1.41), pollen hypersensitivity (17.18), fungi (1.31), keeping pets (1.29), cockroaches (1.69). Conclusion: the prevalence of AR in Chinese children is higher than that in adults, and there are differences in the prevalence of AR in different regions. These 11 risk factors play an important role in the pathogenesis of AR. Early intervention of these risk factors should be carried out in the course of AR prevention and treatment.
【作者单位】：重庆医科大学附属儿童医院耳鼻咽喉头颈外科;
【基金】：重庆市社会事业与民生保障科技创新专项(No:cstc2015shmszx120022) 国家自然科学基金青年基金项目(No:81600781) 重庆医科大学科研培育基金项目(No:201405) 重庆市渝中区科技计划项目(No:20150118)
【分类号】：R765.21

【相似文献】