三维有限元模型分析OSAHS患者下颌不同前伸位置的舌骨位置变化的研究

发布时间：2018-08-23 12:43

【摘要】：目的建立阻塞性睡眠呼吸暂停低通气综合征（OSAHS）患者的上气道及毗邻结构三维有限元模型，通过逐步前伸下颌，观察OSAHS患者舌骨位置的改变及其与下颌前伸量之间的关系，为下颌前伸类口腔矫治器治疗OSAHS的机理研究提供理论依据。方法对OSAHS患者上气道行薄层CT扫描，以DICOM格式输出数据，采用Mimics三维建模软件和Ansys有限元分析软件建立上气道及毗邻结构的三维有限元模型，然后通过加载下颌骨逐步前伸，观察舌骨位置的变化及规律。结果建立了OSAHS患者上气道及毗邻结构的三维有限元模型，定义采用10节点的solid92四面体单元划分网格，按要求划分网格后，，皮质骨、松质骨、肌肉及气道各得到的单元数和节点数分别为：562920、50141、336789个单元，544929、84869、303134个节点。通过逐步前伸下颌骨，舌骨位置向上向前移动，结论应用螺旋CT技术联合使用Mimics三维建模软件，Ansys有限元分析软件建立OSAHS患者上气道及其毗邻结构三维有限元模型，模型的几何相似性较好，使用灵活；通过下颌逐步前伸，对舌骨位置变化进行分析，有效展示下颌骨前伸与舌骨位置变化两者之间关系，证实了研究方法的可行性，为下颌前伸矫治器治疗OSAHS提供理论依据，同时为后续研究OSAHS患者上气道生物力学分析打下良好的基础。
[Abstract]:Objective to establish a three-dimensional finite element model of upper airway and adjacent structure in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). To provide a theoretical basis for the study of the mechanism of mandibular protruding oral appliance in the treatment of OSAHS. Methods the upper airway and adjacent structures of patients with OSAHS were scanned by thin slice CT scanning, and the data were outputted in DICOM format. The 3D finite element models of upper airway and adjacent structures were established by Mimics and Ansys software, and then the mandible was gradually extended forward by loading. The changes and rules of hyoid position were observed. Results the three-dimensional finite element model of upper airway and adjacent structure of OSAHS patients was established. The 10-node solid92 tetrahedron element was used to mesh the cortex bone and cancellous bone. The number of units and nodes of muscle and airway were respectively 5449299,848699,303134 nodes. The position of hyoid bone was moved upward through the progressive extension of mandible. Conclusion the 3D finite element model of upper airway and adjacent structure of OSAHS patients was established by using Mimics 3D modeling software and Ansys finite element analysis software. The geometric similarity of the model is good, and it is flexible to use. Through the analysis of the hyoid position change through the mandibular progressive extension, the relationship between the mandibular forward extension and the hyoid position change is effectively demonstrated, which proves the feasibility of the research method. It provides a theoretical basis for the treatment of OSAHS with mandibular extension appliance and lays a good foundation for further study on biomechanical analysis of upper airway in patients with OSAHS.
【学位授予单位】：宁夏医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R766

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