声治疗与药物治疗慢性耳鸣疗效的Meta分析

发布时间：2018-08-27 19:59

【摘要】：目的比较单纯声治疗与药物治疗慢性耳鸣的疗效。方法通过计算机检索相关期刊论文(CNKI)、万方数据库、维普数据库(VIP)、中国生物医学文献数据库(CBM)、Pubmed、Embase、OVID、SciVerse ScienceDirect和Cochrane library从建库到2017年5月与耳鸣治疗相关文献,按照纳入和排出标准进行筛选,并对其进行严格质量评价和资料提取,采用Revman 5.2软件对纳入文献的总有效率、耳鸣障碍量表(tinnitus handicap inventory,THI)分值和视觉模拟量表(visual analogue scale,VAS)分值进行Meta分析。结果共纳入符合要求的文献16篇,其中,中文文献14篇,英文文献2篇,共计1 594例患者;声治疗组总有效率分别为86.42%(按例数)和80.50%(按耳数),药物治疗组总有效率分别为60.62%(按例数)、48.10%(按耳数),差异均有统计学意义[P0.01(按例数);P0.01(按耳数)]。治疗后声治疗的THI值比治疗前明显下降,且较药物治疗降低更明显(P0.01),治疗后声治疗的VAS值较治疗前明显下降,且较药物治疗降低更明显(P0.05)。结论与药物治疗相比,声治疗能明显提高耳鸣疗效,减轻耳鸣患者症状。
[Abstract]:Objective to compare the effect of simple acoustic therapy and drug therapy on chronic tinnitus. Methods the Chinese periodical full-text database (CNKI), Wanfang database, Weip database (VIP), Chinese biomedical literature database (CBM) PubmedEmbase OVIDE SciVerse ScienceDirect and Cochrane library were searched by computer from the establishment of the database to May 2017 related literature on tinnitus treatment. According to the criteria of inclusion and exclusion, strict quality evaluation and data extraction were carried out. The total effective rate, (tinnitus handicap inventory,THI score of tinnitus disorder scale and (visual analogue scale,VAS score of visual analogue scale were analyzed by Meta with Revman 5.2 software. Results A total of 16 articles were included, including 14 in Chinese and 2 in English, with a total of 1,594 patients. The total effective rates were 86.42% (by cases) and 80.50% (by ears) in sonotherapy group and 60.62% (by cases) in drug treatment group (48.10% by ear number) respectively. The difference was statistically significant [P0.01 (per case) P0.01 (by ear)]. After treatment, the THI value of acoustic therapy was significantly lower than that before treatment, and more significantly lower than that of drug therapy (P0.01). After treatment, the VAS value of acoustic therapy was significantly lower than that before treatment, and the decrease was more obvious than that of drug therapy (P0.05). Conclusion compared with drug therapy, acoustic therapy can significantly improve the efficacy of tinnitus and alleviate the symptoms of tinnitus patients.
【作者单位】：武汉大学人民医院耳鼻咽喉头颈外科;湖北省妇幼保健院耳鼻咽喉科;
【基金】：国家自然科学基金面上项目(81271073) 湖北省自然科学基金(2016CFB661)资助
【分类号】：R764.45

【相似文献】