睡眠呼吸紊乱对交通事故风险影响的meta分析

发布时间：2018-08-29 08:03

【摘要】：目的：综合评价睡眠呼吸紊乱疾病（sleep-disorderedbreathing,SDB）对驾驶员交通事故发生率的影响，探讨是否患有睡眠呼吸紊乱的驾驶员较非睡眠呼吸紊乱驾驶员发生交通事故的风险增加。方法：通过关键词从万方数据库、BIOSISPreviews、Pubmed计算机检索系统检索研究睡眠呼吸紊乱疾病与驾驶员交通事故关系的相关文献，中文检索词包括“睡眠呼吸暂停”、“嗜睡”、“交通事故”和“风险”，，英文检索词包括sleepapnea、sleepiness、drivers、accidents、crashes和risk。并对所获全文的参考文献进行回溯性检索作为补充。按照纳入和排除标准筛选文献、评价质量、提取资料，最后采用ReviewManager5.0软件进行统计学分析。结果：共纳入4项病例对照研究，对合计1459例驾驶员患者和1584例对照驾驶员进行meta分析。结果显示：各研究均支持睡眠呼吸紊乱能增加驾驶员交通事故的风险；meta分析结果表明患有睡眠呼吸紊乱的驾驶员发生交通事故的风险明显高于无睡眠呼吸紊乱的驾驶员[OR=2.17,95%CI(1.41,3.33),P0.05]。结论：与非睡眠呼吸紊乱驾驶员比较，患有睡眠呼吸紊乱的驾驶员发生交通事故的风险增加。
[Abstract]:Objective: to evaluate the influence of sleep apnea disorder (sleep-disorderedbreathing,SDB) on traffic accident rate of drivers, and to explore whether drivers with sleep apnea disorder have higher risk of traffic accidents than non-sleep breathing disorder drivers. Methods: the relevant literatures on the relationship between sleep apnea and drivers' traffic accidents were retrieved from the Bios is Preview / Pubmed computer retrieval system. The Chinese key words include "sleep apnea", "drowsiness", "sleepiness", and "sleep apnea", "sleepiness", "sleep apnea", "drowsiness", and "sleep apnea" in Chinese. "Traffic accident" and "risk", English keywords include sleepapnea,sleepiness,drivers,accidents,crashes and risk. And the full text of the reference for retrospective retrieval as a supplement. According to the inclusion and exclusion criteria, the literature was screened, the quality was evaluated, and the data was extracted. Finally, ReviewManager5.0 software was used for statistical analysis. Results: a total of 4 case-control studies were conducted and meta analysis was performed on 1459 drivers and 1584 control drivers. The results showed that sleep apnea disorder could increase the risk of traffic accident in drivers. The results of meta analysis showed that the risk of traffic accidents in drivers with sleep breathing disorder was significantly higher than that in drivers without sleep apnea disorder [OR=2.17,95%CI (1.41 卤3.33) P 0.05]. Conclusion: compared with drivers with non-sleep apnea disorder, drivers with sleep apnea disorder have an increased risk of traffic accidents.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R766

【引证文献】