突发性聋平坦下降型与全聋型临床特征及实验室指标比较

发布时间：2018-09-07 06:32

【摘要】：目的:探讨突发性聋平坦下降型与全聋型临床特征及实验室指标的异同。方法:对123例突发性聋全频听力下降患者的临床资料进行回顾性分析,观察其中平坦下降型与全聋型患者在性别、年龄、患耳侧别、就诊时间、伴发症状(耳鸣、眩晕)、原有基础疾病(高血压、糖尿病)等临床特征及实验室指标(血小板、凝血系列、D-二聚体、血脂、血液流变学)方面的差异。结果:51例平坦下降型患者男女比例为2.401∶1,72例全聋型患者男女比例为1.058∶1,差异有统计学意义(P0.05);两组患者均以7d之内就诊居多,平坦下降型患者为66.7%,全聋型为83.3%,差异有统计学意义(P0.05);平坦下降型患者伴眩晕仅35.3%,而全聋型高达70.8%,差异有统计学意义(P0.01);两组在年龄分布、患耳侧别、是否伴耳鸣、原有基础疾病(高血压、糖尿病)方面均无差异(P0.05)。在实验室指标方面,平坦下降型患者血小板、血小板压积低于全聋型患者(P0.05),而活化部分凝血活酶时间高于全聋型患者(P0.01),血小板和凝血系列其他指标以及D-二聚体、血脂、血液流变学各项化验数据在两组均无差异(P0.05)。结论:突发性聋全聋型与平坦下降型相比,女性患病率高,更易伴发眩晕,7d内就诊率高,高凝状态者所占比例高。
[Abstract]:Objective: to investigate the clinical features and laboratory indexes of sudden deafness with flat descent type and total deafness type. Methods: the clinical data of 123 patients with sudden deafness with full frequency hearing loss were retrospectively analyzed. Dizziness), differences in clinical features and laboratory parameters (platelet, coagulation series, D-dimer, blood lipid, hemorheology) of underlying diseases (hypertension, diabetes). Results the ratio of male to female to male to female was 2.401: 1 and 72 cases of total deafness were 1.058: 1, the difference was statistically significant (P0.05). The difference was statistically significant (P0.05) in the patients with flat descending type and total deafness type (P 0.05); in flat descending type patients with vertigo was only 35.3, while in all deafness type was up to 70.8, the difference was statistically significant (P0.01); the age distribution of the two groups, the ear side of the affected side, whether or not accompanied by tinnitus, was significant (P0.01). There was no difference in the original basic diseases (hypertension, diabetes) (P0.05). In laboratory indexes, platelets and platelets in patients with flat decline type were lower than those in patients with total deafness type (P0.05), while activated partial thromboplastin time was higher than that in patients with full deafness type (P0.01), other indexes of platelet and coagulation series, D-dimer, blood lipid, There was no difference in the data of hemorheology between the two groups (P0.05). Conclusion: the prevalence of sudden deafness in total deafness type is higher than that in flat descending type, and the rate of treatment within 7 days is higher and the proportion of patients with hypercoagulable state is higher than that of flat deafness type, which is more likely to be accompanied by vertigo within 7 days.
【作者单位】：山西医科大学研究生学院;山西省汾阳医院耳鼻咽喉头颈外科;
【分类号】：R764.437

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