早产儿视网膜病危险因素Meta分析

发布时间：2018-09-08 10:43

【摘要】：目的综合评价早产儿视网膜病(ROP)发生的危险因素,以进行有效的早期筛查。方法检索Cochrane图书馆、Pub Med、MEDLINE、万方数据库、中国学术期刊全文数据库、重庆维普中文科技期刊全文数据库。文献检索起止时间均从建库至2015年10月。统计学分析采用Cochrane协作网提供的Rev Man5.3软件。结果共纳入10篇文献,Meta分析结果显示:胎龄过小[加权均数差(WMD)-1.76;95%CI:-1.98~1.54,P0.01]、输血(OR:3.44;95%CI:2.41~4.90,P0.01)、败血症(OR:2.37;95%CI:1.57~3.57,P0.01)、坏死性小肠结肠炎(NEC)(OR:6.65;95%CI:3.46~12.78,P0.01)、动脉导管未闭(PDA)(OR:2.39;95%CI:1.74~3.29,P0.01)、支气管肺发育不良(BPD)(OR:4.75;95%CI:3.44~6.56,P0.01)、氧疗(OR:2.72;95%CI:1.83~4.05,P0.01)、呼吸窘迫综合征(RDS)(OR:2.53;95%CI:1.70~3.79,P0.01)、窒息(OR:2.99;95%CI:1.72~5.19,P0.01)、低出生体重(WMD-238.19;95%CI:-320.93~155.44,P0.01)有统计学意义。结论胎龄过小、输血、败血症、NEC、BPD、PDA、氧疗、RDS、窒息、低出生体重为ROP发生的危险因素。
[Abstract]:Objective to evaluate the risk factors of retinopathy (ROP) in premature infants and to provide effective early screening. Methods the database of Pub Med,MEDLINE, Wanfang, the full text database of Chinese academic journals and the full text database of Chongqing Weipu Chinese sci-tech periodicals were searched in Cochrane library. The starting and ending time of literature retrieval was from construction to October 2015. The statistical analysis adopts the Rev Man5.3 software provided by Cochrane cooperation network. 缁撴灉鍏辩撼鍏，

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