不同海拔地区藏、汉族阻塞性睡眠呼吸暂停综合征患者血压变异性的比较

发布时间：2018-09-18 16:21

【摘要】：目的:探讨高原两个不同海拔地区藏、汉族阻塞性睡眠呼吸暂停综合征(OSAS)患者血压变异性的特点,初步明确高原缺氧对OSAS患者血压的影响,了解藏、汉族OSAS患者血压变异性是否存在差别。方法:应用多导睡眠图对研究对象进行睡眠呼吸监测,同期进行24h动态血压检查。结果:(1)同一海拔地区藏、汉族OSAS患者24h平均血压、收缩压变异系数、舒张压变异系数较同民族对照组均偏高,差异有统计学意义(P0.05);(2)高海拔地区藏、汉族OSAS患者24h舒张压变异系数较低海拔藏、汉族OSAS患者高,差异有统计学意义(P0.05)。结论:(1)高海拔地区藏、汉族OSAS患者的血压变异性变大,同海拔地区OSAS患者血压变异性无民族差异;(2)与低海拔地区藏、汉族OSAS患者相比,高海拔地区OSAS患者24h舒张压变异系数高。
[Abstract]:Objective: to investigate the characteristics of blood pressure variability in patients with obstructive sleep apnea syndrome (OSAS) in two regions at different altitudes at high altitude, and to determine the effect of hypoxia on blood pressure in patients with OSAS, and to find out the characteristics of blood pressure in patients with obstructive sleep apnea syndrome (OSAS). There is a difference in blood pressure variability in Han OSAS patients. Methods: polysomnography was used to monitor sleep respiration and 24 h ambulatory blood pressure examination. Results: (1) the mean blood pressure, systolic blood pressure variation coefficient and diastolic blood pressure variation coefficient in OSAS patients of Han nationality were higher than those in the control group at the same altitude (P0.05); (2). The variation coefficient of 24 h diastolic blood pressure in Han OSAS patients was higher than that in Han nationality patients with OSAS at low altitude (P0.05). Conclusion: (1) the variability of blood pressure in OSAS patients in high altitude areas is higher than that in OSAS patients at the same altitude. (2) compared with Tibetan and OSAS patients at low altitude, the variability coefficient of 24 h diastolic blood pressure in OSAS patients in high altitude areas is higher than that in OSAS patients in Han nationality.
【作者单位】：青海大学研究生院;保定市第二中心医院;青海省人民医院心内科;
【基金】：青海省科学技术厅应用基础研究计划(No:2014-ZJ-741)
【分类号】：R766

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