EMG修正对颈部及眼部前庭诱发肌源性电位的影响

发布时间：2018-10-04 19:10

【摘要】：目的研究肌电图(electromyogram,EMG)修正对前庭诱发肌源性电位(Vestibular-evoked myogenic po-tentials,VEMPs)结果产生的影响,并建立修正后的cervical Vestibular-evoked myogenic potential(c VEMP)及ocularVestibular Evoked Myogenic Potential(o VEMP)正常值范围,为临床上准确评估前庭感受器功能提供更可靠的参考依据。方法采用500Hz tone-burst刺激声对20名(40耳)听力正常且无耳蜗及前庭系统疾病的正常青年人进行c VEMP及o VEMP测试。受试者年龄为20-30岁,平均年龄(23.76±2.81)岁。测试强度为100d B n HL,通过ER-3A标准插入式耳机给声,测试时体位采取坐姿。结果所有受试者均能引出清晰可重复的c VEMP及o VEMP波形。Tone-burst c VEMP的P1潜伏期为14.13±1.97(ms),N1潜伏期为21.54±2.23(ms),幅值为1.63±0.60(μV)。Tone-burst o VEMP的N1潜伏期为10.15±0.72(ms),P1潜伏期为15.79±1.01(ms),幅值为1.38±1.02(μV)。cVEMP修正前后的振幅有显著性差异(*P0.05),修正前后比值达到40~50倍。结论 EMG修正对振幅标准化有重要意义,其中对c VEMP的测试结果影响较大,建立一组EMG修正后VEMPs的正常参考值范围能够更准确评估双侧不对称性。Tone-burst c VEMP及o VEMP引出率高,可作为临床上评估椭圆囊和球囊功能的常规检测方法。
[Abstract]:Objective to study the effect of electromyography (electromyogram,EMG) correction on vestibular evoked myogenic potential (Vestibular-evoked myogenic po-tentials,VEMPs), and to establish the normal range of cervical Vestibular-evoked myogenic potential (c VEMP) and ocularVestibular Evoked Myogenic Potential (o VEMP). To provide a more reliable reference for the accurate evaluation of vestibular receptor function. Methods c VEMP and o VEMP were measured by 500Hz tone-burst stimulation in 20 normal young people (40 ears) with normal hearing and no disease of cochlea and vestibular system. The subjects were 20-30 years old with an average age of (23.76 卤2.81) years. The test intensity is 100d B n HL, through the ER-3A standard plug-in earphone sound, the test position takes the sitting position. Results all subjects could elicit clear and repeatable c VEMP and o VEMP waveform. Tone-burst c VEMP P1 latency was 14.13 卤1.97 (ms) and N1 latency was 21.54 卤2.23 (ms), amplitude 1.63 卤0.60 (渭 V) .Tone-burst o VEMP N1 latency was 10.15 卤0.72 (ms) VEMP P1 latency was 15.79 卤1.01 (ms), amplitude was 1.38 卤1.02 (渭 V) .cVEMP was significant. Sex difference (P 0.05), the ratio before and after correction reached 40 ~ 50 times. Conclusion EMG correction is of great significance to amplitude standardization, and it has a great influence on the test results of c VEMP. Establishing a normal reference range of VEMPs after EMG correction can more accurately evaluate bilateral asymmetry. Tone-burst c VEMP and o VEMP extraction rate are higher. It can be used as a routine method to evaluate the function of elliptical sac and balloon.
【作者单位】：中国人民解放军总医院耳鼻咽喉头颈外科解放军耳鼻咽喉研究所;聋病防治北京市重点实验室;聋病教育部重点实验室;
【基金】：国家重大科学研究计划项目(2014CB943001) 国家自然科学基金重点项目(81530032) 中国博士后科学基金面上项目(2015M572766)联合资助~~
【分类号】：R764

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