荧光素眼底血管造影术与光学相干断层扫描在原田病诊断中的意义分析

发布时间：2018-10-21 09:41

【摘要】：目的探讨荧光素眼底血管造影术(FFA)与光学相干断层扫描(OCT)联合诊断原田病的价值。方法对湖北科技学院附属眼科医院2014年6月至2017年3月来确诊的原田病患者80例(160眼)的FFA、OTC资料进行回顾性分析,分析FFA和OTC诊断原田病的影像学特征。结果 FFA结合患者的临床症状,正确诊断原田病96眼(60.00%);OCT结合患者的临床表现,正确诊断原田病73眼(45.63%);FFA联合OCT结合患者的临床表现,正确诊断原田病130眼(86.25%)。采用FFA联合OCT诊断原田病与最终确诊结果的符合率高于FFA、OCT单独诊断的符合率(P0.001)。FFA造影观察可见早期患者的脉络膜呈斑驳状、背景荧光强弱不均,早期后极部针尖样高荧光,斑点逐渐扩大,晚期荧光渗漏,在视网膜下汇集呈多湖状强荧光团;OCT检查发现病变区视网膜水肿及神经上皮脱离,表现为下低回声,脱离程度参差不齐,部分腔内可见蓝色反光点。结论 FFA联合OTC可依据早期影像表现对原田病进行早期诊断,为临床诊治提供依据。
[Abstract]:Objective to evaluate the diagnostic value of fluorescein fundus angiography (FFA) combined with optical coherence tomography (OCT) in the diagnosis of Harada disease. Methods the FFA,OTC data of 80 patients (160 eyes) with Harada disease diagnosed from June 2014 to March 2017 in affiliated ophthalmological hospital of Hubei Institute of Science and Technology were analyzed retrospectively. The imaging features of FFA and OTC in diagnosis of Harada disease were analyzed. Results 96 eyes (60.00%) of Harada disease were correctly diagnosed by FFA combined with clinical symptoms. 73 eyes (45.63%) of); FFA combined with OCT were correctly diagnosed, 130 eyes (86.25%) were correctly diagnosed. The coincidence rate of diagnosis of Harada disease with FFA combined with OCT was higher than that of FFA,OCT alone (P0. 001). FFA). The choroidal mottle was observed in early stage patients, the fluorescence intensity of background was uneven, and the peak fluorescence of posterior pole needle in early stage was higher than that of FFA,OCT alone (P0. 001). FFA). The spots gradually expanded, the late fluorescence leakage, and presented as multi-lake hyperfluorescent clusters under the retina. OCT showed that the retinal edema and neuroepithelial detachment in the lesion area showed hypoechoic, and the degree of detachment was uneven. Blue reflectors can be seen in part of the cavity. Conclusion FFA combined with OTC can be used for early diagnosis of Harada disease.
【作者单位】：湖北科技学院眼科;湖北科技学院附属第二医院耳鼻咽喉头颈外科;
【分类号】：R773.9

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