翼状胬肉切除联合自体角膜缘干细胞移植术治疗翼状胬肉47例

发布时间：2018-10-24 14:09

【摘要】：目的:比较单纯使用翼状胬肉切除术和联合自体角膜缘干细胞移植术的临床效果。方法:将94例原发性翼状胬肉进行期患者随机分为两组各47例患者(47眼)。对照组行单纯翼状胬肉切除术;观察组行翼状胬肉切除+自体角膜缘干细胞移植术。测量并比较两组术前,术后1周、1个月及3个月的泪膜破裂时间、角膜散光度、术后3个月后的复发情况、术后并发症及术后主观症状。结果:治疗后,观察组患者复发率6.38%,显著低于对照组患者的23.4%(P0.05)。两组患者泪膜破裂时间及散光度改善程度均与治疗前构成统计学差异,但对照组泪膜破裂时间在术后1周下降幅度高于观察组(P0.05)。两组术后并发症无显著差异;但对照组存在主观不适的患者数量各时期均高于观察组(P0.05)。结论:两术联用治疗翼状胬肉安全性高、疗效较好,值得推广。
[Abstract]:Objective: to compare the clinical effects of pterygium excision combined with limbal stem cell autotransplantation. Methods: 94 patients with primary pterygium were randomly divided into two groups (47 eyes). The control group was treated with simple pterygium excision and the observation group with limbal stem cell transplantation. The tear film rupture time, corneal astigmatism, recurrence after 3 months, postoperative complications and subjective symptoms were measured and compared between the two groups before, 1 week, 1 month and 3 months after operation. Results: after treatment, the recurrence rate of the patients in the observation group was 6.38, which was significantly lower than that in the control group (23.4%) (P0.05). The time of tear film rupture and the degree of improvement of astigmatism in the two groups were significantly different from those before treatment, but the time of tear film rupture in the control group was significantly lower than that in the observation group at 1 week after operation (P0.05). There was no significant difference in postoperative complications between the two groups, but the number of patients with subjective discomfort in the control group was higher than that in the observation group (P0.05). Conclusion: the combined treatment of pterygium is safe and effective, and is worth popularizing.
【作者单位】：贵州省六盘水市人民医院眼科;
【分类号】：R779.6

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