自体游离硬颚黏膜重建眼睑的效果观察

发布时间：2018-11-12 13:49

【摘要】：背景:临床显示自体硬腭黏膜对睑板结膜有较好的替代作用。目的:分析自体游离硬颚黏膜用于眼睑重建的临床效果。方法:纳入180例(180眼)眼睑缺损患者,其中男122例,女58例,年龄10-68岁,均进行自体硬颚黏膜移植修复治疗,眼睑软组织缺损部位采用皮瓣进行修复,治疗后随访观察患者情况及硬腭黏膜情况。结果与结论:所有患者均随访6个月以上。(1)治疗后3个月内,患者硬腭黏膜移植区及结膜囊内产生黏性分泌物,在使用抗生素滴眼液后得到减轻或消失;(2)硬腭黏膜移植片在随访的1年内全部存活,未发生感染或脱落情况,移植片与接受区域之间已有血管长入并局部已与原有组织血管吻合,未发生排斥反应;(3)132例患者自体硬腭黏膜移植片发生不同程度收缩,但眼部正常功能未受到影响;(4)住院期间眼部疼痛等不适症状已有明显减轻,创面未见感染或愈合不良的情况发生;(5)随访期间,8例发生轻度下睑外翻,3例轻度眼睑闭合不全,其余患者眼睑闭合情况及眼睑开闭功能均未见明显异常;(6)除了8例眼球缺失患者,其余患者双眼眼睑的长度差及高度差均在2 mm内;(7)结果表明,自体硬腭黏膜重建眼睑效果良好,具有较好的相容性。
[Abstract]:Background: autologous hard palate mucosa is a good substitute for tarsal conjunctiva. Objective: to analyze the clinical effect of self-free hard jaw mucosa in eyelid reconstruction. Methods: 180 cases (180 eyes) of eyelid defects were included, including 122 males and 58 females, aged 10-68 years. All of them were treated with autogenous hard jaw mucosa transplantation, and the soft tissue defects of eyelids were repaired with flaps. Patients and hard palate mucosa were followed up after treatment. Results and conclusion: all the patients were followed up for more than 6 months. (1) within 3 months after treatment, mucous secretions were produced in the hard palate mucosa transplantation area and conjunctival sac, which were alleviated or disappeared after the use of antibiotic eye drops. (2) all the grafts of hard palate mucosa survived within one year, no infection or shedding occurred, and there was no rejection. (3) in 132 patients, autologous hard palate mucosa grafts contracted to varying degrees, but normal ocular function was not affected. (4) the symptoms of ocular pain and other discomfort have been obviously alleviated during hospitalization, and no infection or poor healing occurred in the wound. (5) during the follow-up period, 8 cases had mild ectropion, 3 cases had mild eyelid insufficiency, and the other patients had no obvious abnormality in eyelid closure and eyelid opening and closing function. (6) except for 8 cases of eye loss, the difference in length and height of eyelid in other patients was within 2 mm. (7) the results showed that the reconstruction of eyelid with autologous hard palate mucosa was effective and had good compatibility.
【作者单位】：河北省眼科医院眼整形泪器病科;河北医科大学第一医院眼科;
【基金】：河北省卫生厅项目(20130589)~~
【分类号】：R77

【相似文献】