生长因子在糖尿病角膜病变的作用

发布时间：2018-11-14 12:04

【摘要】：糖尿病角膜病变是糖尿病患者常见的眼表疾病,也是糖尿病患者失明的原因之一。多种生长因子在糖尿病角膜病变中通过不同途径、不同机制发挥重要作用。目前,关于生长因子对糖尿病角膜病变进展的研究大多是在体外培养和动物实验中进行,也有少量的临床试验。本文回顾了生长因子在维持角膜正常结构和功能及角膜上皮愈合过程中所起的作用,并提出其可能成为临床上治疗糖尿病角膜病变的方法。
[Abstract]:Diabetic keratopathy is a common ocular surface disease in diabetic patients and one of the causes of blindness in diabetic patients. Multiple growth factors play an important role in diabetic keratopathy through different pathways and mechanisms. At present, most of the studies on the progress of diabetic keratopathy by growth factor are carried out in vitro culture and animal experiments, and there are a few clinical trials. This paper reviews the role of growth factor in maintaining the normal structure and function of the cornea and in the process of corneal epithelial healing, and points out that it may be a clinical method for the treatment of diabetic keratopathy.
【作者单位】：湖南省人民医院马王堆院区内分泌科;
【基金】：国家自然科学基金面上项目(81170823) 湖南省科技厅项目(2015JC3118) 湖南省高层次卫生人才“225工程”培养项目资助湖南省卫计委科研计划课题(B2015-70) 湖南省中医药科研计划重点项目(201533)~~
【分类号】：R587.2;R772.2

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