年龄相关性白内障患者眼轴长度与角膜曲率、角膜散光、前房深度和眼压的关系

发布时间：2018-11-15 12:48

【摘要】：目的探讨年龄相关性白内障患者眼轴长度与角膜曲率、角膜散光、前房深度和眼压的关系。方法本次研究对象为在武汉大学中南医院行白内障手术的年龄相关性白内障患者368例(368眼)。患者的眼轴长度、角膜曲率、角膜散光和前房深度均应用IOL-Master(德国蔡司公司)进行测量,眼压采用i Care眼压计测量。使用随机抽样法从不同眼轴长度患者中随机抽出80例(80眼),分别为短眼轴组、中眼轴组和长眼轴组。各组间比较采用单因素方差分析。眼轴长度和角膜曲率、角膜散光、前房深度及眼压的关系采用Spearman相关分析。结果眼轴长度与角膜曲率(r=-0.424,P0.001)、眼轴长度与角膜散光(r=0.138,P=0.008)、眼轴长度与前房深度(r=0.561,P0.001)均相关。其中,眼轴长度与角膜曲率呈负相关,与角膜散光和前房深度呈正相关,但与角膜散光相关性较弱,而与角膜曲率和前房深度中度相关。眼轴长度与眼压无相关性(r=0.064,P=0.326)。中眼轴组和长眼轴组角膜曲率与短眼轴组比较,差异均有统计学意义(均为P0.001);而中眼轴组与长眼轴组差异无统计学意义(P=0.438)。中眼轴组与短眼轴组的角膜散光差异无统计学意义(P=0.333),同样中眼轴组与长眼轴组的角膜散光差异亦无统计学意义(P=0.718),但是短眼轴组与长眼轴组的角膜散光差异有统计学意义(P=0.042)。短眼轴组的前房深度与中眼轴组(P=0.001)和长眼轴组(P0.001)比较差异均有统计学意义,中眼轴组与长眼轴组的前房深度差异亦有统计学意义(P0.001)。3组眼压两两比较差异均无统计学意义(均为P0.05)。结论角膜曲率与眼轴长度呈负相关;角膜散光与眼轴长度相关性弱,只有眼轴长度明显增长,才有可能表现出角膜散光度数增加;前房深度与眼轴长度中等相关,并随眼轴增长而加深;眼轴长度与眼压无相关性。
[Abstract]:Objective to investigate the relationship between axial length and corneal curvature, corneal astigmatism, anterior chamber depth and intraocular pressure in patients with age-related cataract. Methods 368 patients (368 eyes) with age-related cataract underwent cataract surgery in Central and Southern Hospital of Wuhan University. The axial length, corneal curvature, corneal astigmatism and anterior chamber depth were measured by IOL-Master and I Care IOP. Eighty patients (80 eyes) with different axial lengths were randomly selected by random sampling. They were short axis group, middle axis group and long eye axis group. Single factor analysis of variance was used for comparison among groups. The relationship between axial length and corneal curvature, corneal astigmatism, anterior chamber depth and intraocular pressure was analyzed by Spearman correlation. Results the length of eye axis was correlated with corneal curvature (r = 0.424), corneal astigmatism (r ~ (0.138) P ~ (0.008) and anterior chamber depth (r ~ (0.561) P ~ (0.001). Among them, the length of eye axis was negatively correlated with corneal curvature, positively correlated with corneal astigmatism and anterior chamber depth, but weakly correlated with corneal astigmatism, but moderately correlated with corneal curvature and anterior chamber depth. There was no correlation between axial length and intraocular pressure (r = 0.064). There were significant differences in corneal curvature between the middle axis group and the long axis group compared with the short eye axis group (P 0.001), but there was no significant difference between the middle eye axis group and the long eye axis group (P 0. 438). There was no significant difference in corneal astigmatism between the middle axis group and the short axis group (P0. 333), and there was no significant difference in the corneal astigmatism between the middle axis group and the long axis group (P0. 718). But there was significant difference in corneal astigmatism between the short-axis group and the long-axis group (P0. 042). The depth of anterior chamber in the short axis group was significantly different from that in the middle axis group (P0. 001) and the long axis group (P0. 001). There was also significant difference in anterior chamber depth between the middle axis group and the long axial group (P0.001). There was no significant difference in IOP between the 3 groups (P0.05). Conclusion there is a negative correlation between corneal curvature and axial length, and the correlation between corneal astigmatism and axial length is weak, only when the length of ocular axis increases obviously, can the corneal astigmatism degree increase. The depth of anterior chamber was correlated with the length of eye axis and deepened with the increase of eye axis, but there was no correlation between axial length and intraocular pressure.
【作者单位】：武汉大学中南医院眼科;
【分类号】：R776.1

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