低能量冲击波在突发性耳聋综合治疗中的疗效分析
发布时间：2018-12-15 14:39
【摘要】：[目的]对比分析应用低能量冲击波治疗突发性耳聋与传统的治疗方法治疗突发性耳聋,探索新的、有效的突发性耳聋临床治疗方式。[方法]选择2015年6月～2016年8月在昆明医科大学第二附属医院耳鼻喉科确诊为突发性聋并接受住院治疗的99例患者,随机分为A、B、C三组,所有病例均行听力检测(纯音听力检测、声阻抗、ABR)以及相关的影像学检查。A组:常规药物治疗+低能量冲击波治疗:除了常规药物治疗,采用XY-K-SONOTHERA-500体外冲击波治疗仪,以1.8kHz低能量冲击波配合LM号治疗头(内径20mm),冲击点为耳周穴位点,每次治疗冲击波击数标准指引为每个患耳施以1500至2,000击次,至少三个疗程。B组:常规药物治疗+高压氧治疗:除了常规药物治疗,辅助高压氧治疗,连续10 d。C组:常规药物治疗:单纯予以激素静脉滴注、长春西汀静脉滴注、鼠神经生长因子肌注、甲钴胺胶囊口服治疗。[结果]低能量冲击波治疗组与常规药物治疗组比较有统计学意义(P=0.007,P0.01),高压氧治疗组与常规药物组比较有统计学意义(P=0.016,P0.05),低能量冲击波治疗组与高压氧治疗组比较无明显统计学差异(P=1.000,P0.05)。[结论]低能量冲击波治疗组与高压氧治疗组比较无统计学差异,但低能量冲击波治疗突发性聋组明显优于常规药物治疗组,可尝试作为一种新的辅助治疗方式治疗突发性耳聋患者。
[Abstract]:[objective] to explore a new and effective clinical treatment for sudden deafness with low energy shock wave. [methods] from June 2015 to August 2016, 99 patients who were diagnosed as sudden deafness in the Department of Otorhinolaryngology, second affiliated Hospital of Kunming Medical University and admitted to hospital were randomly divided into three groups. All patients underwent audiometry (pure tone audiometry, acoustic impedance, ABR), and related imaging examinations). Group A: conventional drug therapy: low energy shock wave therapy: in addition to routine drug therapy, Using XY-K-SONOTHERA-500 extracorporeal shock wave therapy instrument, 1.8kHz low energy shock wave combined with LM was used to treat head (inner diameter 20mm). The shock point was the point around the ear. The standard guideline of shock wave number per time was 1500 to 2000 beats per affected ear. At least three courses of treatment. Group B: routine drug therapy hyperbaric oxygen therapy: in addition to routine drug therapy, supplementary hyperbaric oxygen therapy, continuous 10 d.C group: routine drug therapy: hormone intravenous drip, vinpocetine intravenous drip, Nerve growth factor (NGF) was injected intramuscularly and methylcobalamin capsule was given orally. [results] there was significant difference between the low energy shock wave treatment group and the routine drug treatment group (P0. 007, P0.01), and the hyperbaric oxygen treatment group was significantly higher than the conventional drug group (P0. 016, P 0.05). There was no significant difference between the low energy shock wave group and the hyperbaric oxygen group (P < 0.05). [conclusion] there is no significant difference between the low energy shock wave group and the hyperbaric oxygen group, but the low energy shock wave group is superior to the routine medicine group in the treatment of sudden deafness. We can try to treat sudden deafness as a new adjuvant therapy.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R764.437
[Abstract]:[objective] to explore a new and effective clinical treatment for sudden deafness with low energy shock wave. [methods] from June 2015 to August 2016, 99 patients who were diagnosed as sudden deafness in the Department of Otorhinolaryngology, second affiliated Hospital of Kunming Medical University and admitted to hospital were randomly divided into three groups. All patients underwent audiometry (pure tone audiometry, acoustic impedance, ABR), and related imaging examinations). Group A: conventional drug therapy: low energy shock wave therapy: in addition to routine drug therapy, Using XY-K-SONOTHERA-500 extracorporeal shock wave therapy instrument, 1.8kHz low energy shock wave combined with LM was used to treat head (inner diameter 20mm). The shock point was the point around the ear. The standard guideline of shock wave number per time was 1500 to 2000 beats per affected ear. At least three courses of treatment. Group B: routine drug therapy hyperbaric oxygen therapy: in addition to routine drug therapy, supplementary hyperbaric oxygen therapy, continuous 10 d.C group: routine drug therapy: hormone intravenous drip, vinpocetine intravenous drip, Nerve growth factor (NGF) was injected intramuscularly and methylcobalamin capsule was given orally. [results] there was significant difference between the low energy shock wave treatment group and the routine drug treatment group (P0. 007, P0.01), and the hyperbaric oxygen treatment group was significantly higher than the conventional drug group (P0. 016, P 0.05). There was no significant difference between the low energy shock wave group and the hyperbaric oxygen group (P < 0.05). [conclusion] there is no significant difference between the low energy shock wave group and the hyperbaric oxygen group, but the low energy shock wave group is superior to the routine medicine group in the treatment of sudden deafness. We can try to treat sudden deafness as a new adjuvant therapy.
【学位授予单位】：昆明医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R764.437
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相关期刊论文 前10条
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