鼻内镜下低温等离子与电动吸割器治疗腺样体肥大疗效比较的Meta分析

发布时间：2018-12-18 16:08

【摘要】：目的:评价鼻内镜辅助下低温等离子(endoscopic assisted low temperature plasma,ELTP)与电动吸割器(electric planer,EP)治疗腺样体肥大疗效的差异。方法:计算机检索中国知网,万方数据库,维普数据库,中国生物医学文献数据库,PubMed,Embase和Cochrane数据库,查找有关ELTP与EP切除腺样体疗效对比的随机对照研究。检索时限为2007年1月至2016年6月。对纳入的文献进行方法学评价,并用Revman 5.2软件对符合标准的研究进行Meta分析。结果:最终纳入13个随机对照研究,共1 448名患者,其中722名患者接受ELTP手术,即ELTP组,726名患者接受EP手术,即EP组。Meta分析结果示:与EP手术相比,ELTP手术的总体有效率明显提高(OR=3.19,95%CI:1.42~7.15),P=0.005],并且术中出血量明显减少(MD= 20.35,95%CI: 20.84~ 19.87,P0.001),手术时间明显缩短(MD= 15.71,95%CI: 18.06~ 12.17,P0.001),并发症的发生率也明显降低(OR=0.13,95%CI:0.06~0.30,P0.001);而两组术中圆枕损伤发生率、术后腺样体残留及术后出血发生率差异无统计学意义。结论:相比于EP,ELTP在腺样体肥大手术中更具有优势。
[Abstract]:Objective: to evaluate the difference between endoscopic low temperature plasma (endoscopic assisted low temperature plasma,ELTP) and electric aspiration (electric planer,EP) in the treatment of adenoid hypertrophy. Methods: a randomized controlled study on the comparison of the effects of adenoidectomy with ELTP and EP was carried out by computer searching the database of Chinese Zhiwang, Wanfang database, Weip database, Chinese biomedical literature database, PubMed,Embase database and Cochrane database. The time limit for retrieval is from January 2007 to June 2016. The methodological evaluation of the included literature was carried out, and the Meta analysis of the compliant research was carried out with Revman 5.2 software. Results: a total of 1 448 patients were enrolled in 13 randomized controlled trials, of which 722 patients underwent ELTP operation, that is, ELTP group, and 726 patients underwent EP operation, that is, EP group. The results of Meta analysis showed that compared with EP operation, 726 patients underwent EP operation. The overall effective rate of ELTP operation was significantly improved (OR=3.19,95%CI:1.42~7.15, P0. 005), and the amount of intraoperative bleeding was decreased (MD= 20. 35% 95 CI: 20. 84 ~ 19. 87% P0.001). The operative time was significantly shortened (MD= 15.71 / 95 CI: 18.06 ~ 12.17 / P0.001), and the incidence of complications (OR=0.13,95%CI:0.06~0.30,P0.001) was also significantly reduced (P < 0.05). There was no significant difference between the two groups in the incidence of occipital injury, postoperative adenoid residue and postoperative hemorrhage. Conclusion: compared with EP,ELTP, it has more advantages in adenoid hypertrophy surgery.
【作者单位】：中南大学湘雅医院耳鼻咽喉头颈外科耳鼻咽喉科重大疾病研究湖南省重点实验室;
【基金】：国家重点基础研究计划发展项目(2014CB943003) 国家自然科学基金(81300819,81170912)~~
【分类号】：R766.9

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